慢性阻塞性肺疾病合并心房颤动的研究进展  

Advances in chronic obstructive pulmonary disease with atrial fibrillation

作　　者：韩雪梅[1] 赵志强(综述)[2] 赖雁平[1] 曹杉(审校) HAN Xuemei;ZHAO Zhiqiang;LAI Yanping;CAO Shan(Department of Respiratory and Critical Care Medicine,the Second Hospital of Tianjin Medical University,Tianjin 300211,China;Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease/Tianjin Institute of Cardiology/Department of Cardiology,the Second Hospital of Tianjin Medical University,Tianjin 300211,China)

机构地区：[1]天津医科大学第二医院呼吸与危重症医学科,天津300211 [2]天津市心血管病离子与分子机能重点实验室/天津心脏病学研究所/天津医科大学第二医院心脏科,天津300211

出　　处：《重庆医学》2022年第5期868-873,共6页Chongqing medicine

基　　金：国家自然科学基金面上项目(81370300);天津市卫生健康委员会科技项目(ZC20143);天津医科大学第二医院重点实验室基金项目(2019ZDSYS05)。

摘　　要：慢性阻塞性肺疾病(COPD)在心房颤动(房颤)患者中广泛存在,流行病学显示COPD在房颤患者中的发病率很高,约为23%。二者有着共同的危险因素,且增加了该人群的总体发病率和病死率。此外,COPD可能会促进房颤治疗的复杂化。房颤患者COPD的诊断和治疗需要心内科和呼吸内科医师之间密切的跨学科合作。其鉴别诊断可能具有挑战性,肺功能评价及测定脑利钠肽和超声心动图可能是检测COPD和心力衰竭导致呼吸困难的常规方法。然而,目前尚不清楚COPD治疗是否能改善房颤的预后,以及用哪种指标来判断COPD的严重程度和指导房颤患者的治疗。未来对房颤患者需要进行前瞻性队列研究,以确认COPD和房颤之间的关系,以及COPD或房颤治疗的临床获益。Chronic obstructive pulmonary disease(COPD)is widespread in the patients with atrial fibrillation.Epidemiology shows that the incidence of COPD in the patients with atrial fibrillation is very high,estimated at 23%.Both have common risk factors and increase the overall morbidity and mortality of the population.Additionally,COPD may complicate the treatment of atrial fibrillation.The diagnosis and treatment of COPD in the atrial fibrillation patients requires a close interdisciplinary collaboration between the cardiologist and pulmonologist.Its differential diagnosis may be challenging.Routine evaluation of lung function,determination of brain natriuretic peptides and echocardiography may be reasonable to detect COPD and heart failure as contributing the causes of dyspnoea.However,it is not clear whether COPD treatment can improve the prognosis of atrial fibrillation,and which indicator is used to judge the severity of COPD and guide the treatment of patients with atrial fibrillation.Future prospective cohort studies in the atrial fibrillation patients are needed to confirm the relationship between COPD and atrial fibrillation,and the clinical benefits of treatment of either COPD or atrial fibrillation.

关 键 词：慢性阻塞性肺疾病 心房颤动 肺功能 超声心动图 综述 

分 类 号：R563.3[医药卫生—呼吸系统]