鸭疫里默氏杆菌耐药现状及耐药机制研究进展  

Research Progress on Antimicrobial Resistance and Resistance Mechanism of Riemerella anatipestifer

作　　者：关椿久 朱寅初 郑雪 杨华[2] 叶宏伟 刘璨颖 唐标[2] GUAN Chunjiu;ZHU Yinchu;ZHENG Xue;YANG Hua;YE Hongwei;LIU Canying;TANG Biao(School of Life Science and Engineering,Foshan University,Foshan,Guangdong 5280001;Institute of Agro-products Safety and Nutrition,Zhejiang Academy of Agricultural Sciences,Hangzhou,Zhejiang 310021;Institute of Animal Husbandry and Veterinary Medicine,Zhejiang Academy of Agricultural Sciences,Hangzhou,Zhejiang 310021;Agricultural and Forestry Technology Extension Center of Lin′an District,Hangzhou City,Hangzhou,Zhejiang 311399)

机构地区：[1]佛山科学技术学院生命科学与工程学院,广东佛山5280001 [2]浙江省农业科学院农产品质量安全与营养研究所,浙江杭州310021 [3]浙江省农业科学院畜牧兽医研究所,浙江杭州310020 [4]杭州市临安区农林技术推广中心,浙江杭州311399

出　　处：《中国家禽》2022年第2期87-95,共9页China Poultry

基　　金：浙江省重点研发计划项目(2020C02031);国家自然科学基金青年科学基金项目(31700007);省部共建农产品质量安全危害因子与风险防控国家重点实验室项目(2010DS700124-ZZ2008);浙江省农业重大技术协同推广计划(2021XTTGXM03-3)。

摘　　要：鸭疫里默氏杆菌作为常见的水禽病原体之一,能够引发鸭、鹅等鸭疫里默氏杆菌病,该病分布广泛,传播迅速且死亡率高。虽然抗生素有效减少了该病带来的经济损失,但是由于抗生素在治疗和促生长过程中的大量使用,导致鸭疫里默氏杆菌的耐药性正在逐年升高。文章就鸭疫里默氏杆菌对大环内酯类、氨基糖苷类、四环素类等抗生素,特别是替加环素的耐药性以及耐药机制进行系统分析,以期能对鸭疫里默氏杆菌病的防治提供理论依据。As a common waterfowl pathogen,Riemerella anatipestifer can cause Riemerella anatipestifer disease in ducks and geese.The disease is widely distributed,spreads rapidly and has a high mortality rate.Although antibiotics effectively reduce the economic loss caused by the disease,due to the extensive use of antibiotics in treatment and growth promotion process,the antimicrobial resistance of Riemerella anatipestifer is increasing year by year.This paper were systematically analyzed the resistance and mechanism of macrolides,aminoglycosides and tetracyclines,especially tigecycline,in order to provide theoretical basis for the prevention and treatment of Riemerella anatipestifer disease.

关 键 词：鸭疫里默氏杆菌 流行 耐药性 耐药基因 

分 类 号：S855.1[农业科学—临床兽医学]