2019冠状病毒病爆发期间城市居民午睡与抑郁情绪的关系研究  

Association between napping status and depressive symptoms in urban residents during the COVID-19 epidemic

作　　者：林文慧 白冠男 何威 杨菲 李伟 闵燕 LU Ying HSING Ann 朱善宽[1] LIN Wenhui;BAI Guannan;HE Wei;YANG Fei;LI Wei;MIN Yan;LU Ying;HSING Ann;ZHU Shankuan(School of Public Health,Zhejiang University,Hangzhou 310058,China;Children’s Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,National Children’s Regional Medical Center,Hangzhou 310052,China;Department of Epidemiology and Population Health,Stanford University School of Medicine,Stanford 94305,USA;Department of Biomedical Data Science,Stanford University School of Medicine,Stanford 94305,USA)

机构地区：[1]浙江大学公共卫生学院,浙江杭州310058 [2]浙江大学医学院附属儿童医院国家儿童健康与疾病临床医学研究中心国家儿童区域医疗中心,浙江杭州310052 [3]美国斯坦福大学医学院流行病学与人口健康学系,美国斯坦福943054 [4]美国斯坦福大学医学院生物医学数据科学系,美国斯坦福94305

出　　处：《浙江大学学报（医学版）》2021年第6期741-747,共7页Journal of Zhejiang University(Medical Sciences)

基　　金：纽崔莱资助斯坦福大学WELL项目基金(519000-X11501);浙江大学教育基金(100000-11320);唐仲英基金(419600-11102);Hsun K Chou基金(419600-11107)。

摘　　要：目的:探索2019冠状病毒病(COVID-19)爆发期间城市居民午睡与抑郁情绪的关系,为突发公共卫生事件期间城市居民抑郁情绪的预防提供科学依据。方法:基于WELL中国队列人群,于2020年4月8日至2020年5月29日通过电话访谈获取COVID-19爆发期间被调查者的健康与生活方式信息,最终纳入3075名18~80岁杭州市拱墅区城市居民的调查资料。采用世界卫生组织五项身心健康指标测量抑郁情绪,多元logistic回归模型分析调查对象午睡状况与抑郁情绪的关系。结果:COVID-19爆发期间约有20.6%的城市居民出现抑郁情绪;在一般人群中,有午睡行为尤其是午睡时长不超过30 min与抑郁情绪发生风险(OR=0.61,95%CI:0.47~0.79,P<0.01)、新发抑郁情绪风险(OR=0.66,95%CI:0.50~0.88,P<0.01)较低相关;在有抑郁情绪的城市居民中,仅午睡时长不超过30 min有利于抑郁情绪改善(OR=0.42,95%CI:0.21~0.82,P<0.05)。结论:2019冠状病毒病爆发期间,约有1/5的城市居民存在抑郁情绪,短时间的午睡可能是抑郁情绪的保护因素。Objective: To explore the association between napping status and depressive symptoms in urban residents during the coronavirus disease 2019(COVID-19) epidemic.Methods: The survey was embedded in the Wellness Living Laboratory-China(WELL China) cohort study. Health and lifestyle information during the COVID-19 epidemic were obtained via the telephone interview from April 8, 2020 to May 29, 2020. A total of 3075 residents aged 18 to 80 years from Gongshu district of Hangzhou city with complete data were included in the analyses. The World Health Organization-Five Well-being Index(WHO-5) was used to measure depressive symptoms. Multiple logistic regression model was used to assess the association between napping status and depressive symptoms in the participants.Results: The prevalence of depressive symptoms was 20.6% in the participants during the COVID-19 epidemic. Daytime napping behavior, especially napping time ≤30 min, was associated with a lower risk of prevalent depressive symptoms(OR=0.61, 95%CI: 0.47–0.79,P<0.01) and incident depressive symptoms in the population(OR=0.66, 95%CI: 0.50–0.88,P<0.01). Among those with depressive symptoms at baseline, napping time ≤ 30 min was beneficial for the outcome of depressive symptoms(OR=0.42, 95%CI: 0.21–0.82,P<0.05).Conclusion: One in five urban residents have depressive symptoms during the COVID-19 epidemic, and a short nap during the day may be a protective factor against depressive symptoms.

关 键 词：2019冠状病毒病 抑郁情绪 午睡 城市居民 队列研究 

分 类 号：R183.3[医药卫生—流行病学] R749.055[医药卫生—公共卫生与预防医学]