DNA信息存储的机遇与挑战  

The opportunities and challenges in DNA digital data storage

作　　者：强薇 沈玥 戴俊彪 QIANG Wei;SHEN Yue;DAI Jun-Biao(Guangdong Provincial Key Laboratory of Synthetic Genomics and Shenzhen Key Laboratory of Synthetic Genomics,Institute of Synthetic Biology,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen 518055,China;Guangdong Provincial Key Laboratory of Genome Read and Write,BGI-Shenzhen,Shenzhen,518083,China)

机构地区：[1]中国科学院深圳先进技术研究院,深圳合成生物学创新研究院,广东省合成基因组学重点实验室,深圳市合成基因组学重点实验室,深圳518055 [2]深圳华大生命科学研究院,广东省高通量基因组测序与合成编辑应用实验室,深圳518083

出　　处：《生命科学》2021年第12期1469-1475,共7页Chinese Bulletin of Life Sciences

基　　金：广东省合成基因组学重点实验室(2019B030301006)。

摘　　要：在高度信息化的现代社会中,现有的硅基存储资源将难以满足爆炸式增长的信息总量。基于DNA介质的信息存储融合了多个学科领域,提供了一种新的存储模式,并在世界范围内取得了相当的进展。该文首先对目前DNA信息存储所取得的进展进行梳理归纳,继而总结了DNA信息领域现阶段所面临的关键问题,最后对DNA信息存储领域未来进行展望,以期为下一步研究提供方向。In modern society,the amount of information is exploding.However,current silicon-based storage is limited by the availability of the materials and quickly behinds the needs.Storing information in DNA is an interdisciplinary filed,which has the potential to provide a solution for the increased information.The filed has made many achievements in the past decade.Here,we start the review by briefly introducing the progress of the field and highlighting a few recent achievements.Next,we focus our attention on bottlenecks which are currently limiting the application of DNA data storage and discuss potential solutions.Finally,future directions are proposed.

关 键 词：DNA存储 合成生物学 信息科学 生物信息学 高通量DNA合成 

分 类 号：Q811.4[生物学—生物工程]