HIV阳性肛周脓肿患者临床病理特征分析  

An Analysis on the Clinical Pathological Features of HIV+Patients with Perianal Abscess

作　　者：王蕾[1] 苏华斌 肖冠英 WANG Lei;SU Hua-bin;XIAO Guan-ying(Guangzhou Eighth People's Hospital,Guangzhou Medical University,Guangzhou,Guangdong 510000)

机构地区：[1]广州医科大学附属市八医院,广东广州510000

出　　处：《中国肛肠病杂志》2021年第12期22-23,共2页Chinese Journal of Coloproctology

基　　金：广东省医学科学技术研究基金项目(A2017472)。

摘　　要：为探讨人类免疫缺陷病毒(HIV)阳性肛周脓肿患者临床病理特征,为临床合理使用抗生素提供依据。回顾分析132例HIV阳性肛周脓肿患者的临床资料。结果显示,132例HIV阳性肛周脓肿患者中,除急性化脓性炎症外,合并尖锐湿疣30例,传染性软疣1例,结核3例,马尔尼菲蓝状菌感染5例。8例肛周脓肿组织中检出梅毒螺旋体,合并高级别鳞状上皮内病变1例,鳞状细胞癌1例。结果表明,HIV阳性肛周脓肿患者除了常见细菌感染外,容易合并病毒、结核、真菌和梅毒螺旋体感染。因此对于HIV阳性肛周脓肿患者除常规行细菌培养和药敏分析外,还应重视抗酸染色、六胺银、PAS和免疫组化等检测,以明确是否有结核、真菌及其他病原体感染,从而更有效指导临床使用药物,改善患者预后。This study was to investigate the clinical pathological feature of HIV+patients with perianal abscess,so as to provide basis for rationally using antibiotics,reviewed and analysed the clinical data of 132 HIV+patients with perianal abscess.As results,in the 132 cases except acute purulent inflammation,complicated with pointed wart in 30 cases,with infectious molluscum in 1 case,with tuberculosis in 3 cases,5 cases suffered from infection of Talaromyces marneffei.Treponema pallidum was detected from the perianal abscess tissue of 8 cases,complicated with high-grade intrasquamous lesion in 1 case,with squamous cancer in 1 case.Resutls show that in HIV+patients with perianal abscess except common bacterial infection,are also infected with virus,tuberculosis,fungus,and Treponema pallidum,due to which clinically,except routine bacterial culture and drug-sensitivity analysis,also acid-fast bacillus stain,GMSll stain,PAS and immuno-histo-chemistry detection should be taken,so as to determine whether tuberculosis,fungus,and other pathgens infection,just more effectively using autibiotics clinically,with improving patients’ prognosis.

关 键 词：肛周脓肿 HIV 病理特征 

分 类 号：R512.91[医药卫生—内科学] R657.15[医药卫生—临床医学]