补肾活血法辅助治疗薄型子宫内膜不孕症临床研究  

Clinical Study on Kidney-Tonifying and Blood-Activating Method for Thin Endometrial Infertility

作　　者：张迎春 刘伟娜 朱艳菊 ZHANG Yingchun;LIU Weina;ZHU Yanju

机构地区：[1]平顶山市计划生育科学技术研究所(平顶山计生医院),河南平顶山467000

出　　处：《新中医》2022年第1期119-123,共5页New Chinese Medicine

摘　　要：目的:观察补肾活血法辅助治疗薄型子宫内膜不孕症的疗效及对患者子宫内膜厚度、相关激素指标及内膜血流水平的影响。方法:选取103例薄型子宫内膜不孕症患者作为研究对象,依据治疗方案不同分为对照组51例和观察组52例。对照组给予芬吗通片治疗,观察组在对照组基础上给予补肾活血方治疗。比较2组临床疗效,检测治疗前后子宫内膜厚度、激素水平、内膜血流参数,统计排卵率及妊娠率。结果:观察组总有效率为92.31%,高于对照组74.51%,差异有统计学意义(P<0.05)。治疗后,2组黄体中期子宫内膜厚度较治疗前升高,且观察组高于对照组,差异有统计学意义(P<0.05)。治疗后,2组黄体中期血清孕酮(P)、雌二醇(E_(2))水平较治疗前均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。治疗后,2组黄体中期阻力指数(RI)、搏动指数(PI)、收缩末期峰值与舒张末期峰值的比值(S/D)较治疗前均降低,且观察组低于对照组,差异有统计学意义(P<0.05)。2组排卵率和妊娠率比较,差异无统计学意义(P>0.05)。结论:补肾活血法辅助治疗薄型子宫内膜不孕症患者,通过促进子宫内膜生长发育,调节子宫内膜厚度,改善性欲淡漠、腰膝酸软等临床症状,调节相关激素指标和内膜血流水平,提高临床疗效。Objective:To observe the curative effect of kidney-tonifying and blood-activating method for thin endometrial infertility and its effect on endometrial thickness,related hormone indexes and endometrial blood flow levels.Methods:A total of 103 cases of patients with thin endometrial infertility were selected as the study subjects,and divided into the control group and the observation group according to the treatment regimens,with 51 and 52 cases respectively.The control group was treated with femoston tablets,and the observation group was additionally treated with kidney-tonifying and bloodactivating prescription based on the treatment of the control group.The clinical effects in the two groups were compared.Before and after treatment,the endometrial thickness,hormones levels and endometrial blood flow parameters were detected,and the ovulation rates and pregnancy rates were counted.Results:The total effective rate was 92.31%in the observation group,higher than that of 74.51%in the control group,the difference being significant(P<0.05).After treatment,the endometrial thickness in luteal middle phase in the two groups was increased when compared with that before treatment,and the one in the observation group was higher than that in the control group,the difference being significant(P<0.05).After treatment,the levels of phosphorus(P)and estrogen(E_(2))in serum in luteal middle phase in the two groups were increased when compared with those before treatment,and the levels in the observation group were higher than those in the control group,the difference being significant(P<0.05).After treatment,the resistance index(RI),pulsatility index(PI),ratio of end-diastolic peak to end-systolic peak(S/D)in luteal middle phase in the two groups were decreased when compared with those before treatment,and the indexes in the observation group were lower than those in the control group,the difference being significant(P<0.05).There was no significant difference being found in the comparison of ovulation rates and pregnancy rates b

关 键 词：薄型子宫内膜不孕症 补肾活血法 芬吗通片 子宫内膜厚度 激素 内膜血流参数 

分 类 号：R711.6[医药卫生—妇产科学]