经导管主动脉瓣置换术对重度主动脉瓣狭窄初步效果  

CLINICAL EFFECT OF TRANSCATHETER AORTIC VALVE IMPLANTATION IN TREATMENT OF SEVERE AORTIC STENOSIS: A PRELIMINARY STUDY

作　　者：李磊 牛兆倬 吕海辰 邓宏博 池一凡 LI Lei;NIU Zhaozhuo;L Haichen;DENG Hongbo;CHI Yifan(Department of Heart Center,Dalian Medical University Qingdao Municipal Hospital,Qingdao 266071,China)

机构地区：[1]大连医科大学附属青岛市市立医院心脏中心,山东青岛266071 [2]青岛市海慈医院心外科

出　　处：《青岛大学学报（医学版）》2022年第1期115-118,共4页Journal of Qingdao University(Medical Sciences)

基　　金：国家自然科学基金青年科学基金项目(81700245)。

摘　　要：目的分析经导管主动脉瓣置换术(TAVI)治疗重度主动脉瓣狭窄(AS)的效果。方法收集TAVI治疗重度AS病人11例的临床资料,分析其基线数据、围术期情况及近期预后。结果 TAVI手术成功率100%,术后病人均顺利出院。病人术后平均主动脉瓣跨瓣压差由(6.32±1.97)kPa下降至(1.34±0.24)kPa, 7例病人出现轻微瓣周漏,3例病人术后发生严重的房室传导阻滞行永久起搏器置入。术后30 d病人均无症状生存。结论应用TAVI治疗高危重度AS病人是安全有效的。Objective To investigate the clinical effect of transcatheter aortic valve implantation(TAVI) in the treatment of patients with severe aortic stenosis(AS). Methods Clinical data were collected from 11 patients with severe AS who underwent TAVI, and their baseline data, perioperative conditions, and short-term prognosis were analyzed. Results The success rate of TAVI surgery was 100%, and all patients were discharged successfully. The mean pressure gradient of the aortic valve decreased from(6.32±1.97) kPa to(1.34±0.24) kPa after surgery. Mild perivalvular leakage was observed in 7 patients, and 3 patients required the implantation of a permanent pacemaker due to severe atrioventricular block after surgery. All the patients survived without any symptom for 30 days after surgery. Conclusion TAVI is safe and effective in the treatment of high-risk patients with severe AS.

关 键 词：经导管主动脉瓣置换 主动脉瓣狭窄 预后 

分 类 号：R654.27[医药卫生—外科学] R542.52[医药卫生—临床医学]