疏肝补肾汤加减联合温针灸治疗腰椎间盘源性腰痛(气滞血瘀型)的疗效及对腰椎功能、炎症因子水平的影响  

Curative effect of Shugan Bushen Decoction combined with warm needle moxibustion in treating lumbar discogenic low back pain(Qi stagnation and blood stasis type)and its effect on lumbar vertebral function and inflammatory factor levels

作　　者：王彦鹏 郝龙飞 赵晓芸 WANG Yan-peng;HAO Long-fei;ZHAO Xiao-yun(Second Department of Orthopedics and Traumatology,the Traditional Chinese Medicine Hospital of Shaanxi Province,Xi'an 710003,Shaanxi,CHINA)

机构地区：[1]陕西省中医医院骨伤二科,陕西西安710003

出　　处：《海南医学》2022年第5期563-566,共4页Hainan Medical Journal

摘　　要：目的探讨疏肝补肾汤加减联合温针灸治疗腰椎间盘源性腰痛(气滞血瘀型)的疗效及对腰椎功能、炎症因子水平的影响。方法选取2020年4月至2021年4月于陕西省中医医院治疗的96例腰椎间盘源性腰痛(气滞血瘀型)患者为研究对象,依据随机单双数法分为对照组与联合组各48例。对照组患者采用温针灸治疗,联合组患者在对照组治疗的基础上采用疏肝补肾汤治疗。治疗1个月后,比较两组患者的临床疗效、治疗前后腰椎活动度(ROM)、Oswestry功能障碍指数(ODI)、日本骨科协会评分(JOA),以及肿瘤坏死因子-α(TNF-α)、白介素-4(IL-4)和白介素-6(IL-6)水平。结果联合组患者的治疗总有效率为91.67%,明显高于对照组的70.83%,差异有统计学意义(P<0.05);治疗前,两组患者的ROM、ODI、JOA评分比较差异均无统计学意义(P>0.05);治疗后,联合组患者的ROM、ODI评分分别为(2.05±0.45)分、(5.16±1.28)分,明显低于对照组的(6.62±1.88)分、(11.61±2.62)分,JOA评分为(26.12±3.03)分,明显高于对照组的(20.27±2.18)分,差异均有统计学意义(P<0.05);治疗前,两组患者的TNF-α、IL-4、IL-6水平比较差异均无统计学意义(P>0.05);治疗后,联合组患者的TNF-α、IL-4、IL-6水平分别为(119.96±18.92)ng/L、(2.09±0.54)ng/L、(6.73±1.50)ng/L,明显低于对照组的(156.36±19.95)ng/L、(4.04±0.77)ng/L、(8.61±1.52)ng/L,差异均具有统计学意义(P<0.05)。结论疏肝补肾汤加减联合温针灸治疗腰椎间盘源性腰痛(气滞血瘀型)可明显改善患者的腰椎功能及炎症因子水平,临床治疗效果显著,值得推广应用。Objective To explore the curative effect of Shugan Bushen Decoction combined with warm needling moxibustion in the treatment of lumbar discogenic low back pain(Qi stagnation and blood stasis type)and its effect on lumbar vertebral function and inflammatory factor levels.Methods A total of 96 patients with lumbar discogenic low back pain(Qi stagnation and blood stasis type)treated in the Traditional Chinese Medicine Hospital of Shaanxi Province from April 2020 to April 2021 were selected as the research subjects.According to the random odd and even number method,the patients were divided into the control group and the combination group,each with 48 patients.Patients in the control group were treated with warm acupuncture and moxibustion,and those in the combination group were treated with Shugan Bushen Decoction on the basis of the control group.After 1 month of treatment,the clinical efficacy and lumbar mobility(ROM),Oswestry dysfunction index(ODI),Japanese Orthopedic Association score(JOA),tumor necrosis factor-α(TNF-α),interleukin-4(IL-4),interleukin-6(IL-6)were compared between the two groups before and after treatment.Results The total effective rate of the combination group was 91.67%,which was significantly higher than 70.83%of the control group(P<0.05).Before treatment,there was no significant difference in ROM,ODI,and JOA scores between the two groups(P>0.05);after treatment,the ROM and ODI scores of the combination group were(2.05±0.45)points and(5.16±1.28)points,which were significantly lower than(6.62±1.88)points and(11.61±2.62)points of the control group;the JOA score was(26.12±3.03)points,which was significantly higher than(20.27±2.18)points of the control group;the differences were statistically significant(P<0.05).Before treatment,there was no significant difference in the levels of TNF-α,IL-4,and IL-6 between the two groups(P>0.05);the levels of TNF-α,IL-4,and IL-6 in the combination group were(119.96±18.92)ng/L,(2.09±0.54)ng/L,(6.73±1.50)ng/L,which were significantly lower than(156.3

关 键 词：腰椎间盘源性腰痛 气滞血瘀 疏肝补肾汤 温针灸 疗效 腰椎功能 肿瘤坏死因子-α 白介素-4 白介素-6 

分 类 号：R681.53[医药卫生—骨科学]