RTS评分、D-乳酸、DAO在创伤性骨折并休克中的评估意义  

The evaluation significance of RTS score,D-lactic acid and DAO in traumatic fracture and shock

作　　者：丁丁[1] 赵志坚[1] 陈坤峰[1] DING Ding;ZHAO Zhijian;CHEN Kunfeng(Department of Emergency Traumatology,the First People􀆳s Hospital of Shangqiu City,Shangqiu,Henan,China,476100)

机构地区：[1]商丘市第一人民医院急诊创伤外科,河南商丘476100

出　　处：《分子诊断与治疗杂志》2022年第2期266-269,共4页Journal of Molecular Diagnostics and Therapy

基　　金：河南省医学科技攻关计划项目(LHGJ20190912)。

摘　　要：目的分析修正创伤分数(RTS)评分、D-乳酸、二胺氧化酶(DAO)在创伤性骨折并休克中的评估意义。方法收集商丘市第一人民医院2018年4月至2020年12月收治的174例创伤性骨折患者,其中并发休克者93例(研究组),未并发休克者81例(对照组)。比较两组RTS评分及D-乳酸、DAO水平。分析创伤性骨折并休克患者预后情况,比较不同预后患者RTS、APACHEⅡ评分及D-乳酸、DAO水平;采用Pearson法分析上述因子与APACHEⅡ评分相关性。绘制受试者工作特征曲线(ROC),分析RTS评分、D-乳酸、DAO水平对创伤性骨折并休克患者预后的评估价值。结果研究组RTS评分及D-乳酸、DAO水平均显著高于对照组,差异有统计学意义(P<0.05)。93例并发休克患者中,预后死亡30例(死亡组),预后生存63例(生存组)。死亡组RTS、APACHEⅡ评分及D-乳酸、DAO水平均显著高于生存组,差异有统计学意义(P<0.05)。相关性分析结果示,RTS评分、D-乳酸、DAO水平与APACHEⅡ评分均呈正相关关系(P<0.05)。ROC曲线分析结果显示,三者联合评估的AUC、敏感度、特异度分别为0.893、0.889、0.912,均明显高于单一检测(P<0.05)。结论创伤性骨折并休克患者RTS评分明显增高,D-乳酸、DAO水平呈异常表达,且与APACHEⅡ具有一定相关性,可作为临床评估患者病情、预后的辅助指标。Objective To analyze the evaluation significance of Revised trauma score(RTS score,D-lactic acid,and Diamine oxidase(DAO)in traumatic fracture and shock. Methods The clinical data of 174 traumatic fracture patients admitted to the First People’s Hospital of Shangqiu City from April 2018 to December 2020 were collected,including 93 patients with shock(study group)and 81 patients without shock(control group). The RTS scores,D-lactic acid and DAO levels between the two groups were compared. The prognosis of patients with traumatic fracture and shock was analyzed,and the RTS,APACHEⅡ score,D-lactic acid and DAO levels of patients with different prognosis were compared. Pearson method was used to analyze the correlation between the above factors and APACHEⅡ score. The receiver operating characteristic curve(ROC)was drawn to analyze the evaluation value of RTS score,D-lactic acid,and DAO level on prognosis of patients with traumatic fracture and shock. Results The RTS score,D-lactic acid and DAO levels of the study group were significantly higher than those of the control group,and the difference was statistically significant(P<0.05). Among the 93 patients with shock,30 died(death group),and 63 survived(survival group). The RTS,APACHE Ⅱ scores,D-lactic acid and DAO levels in the death group were significantly higher than those in the survival group,and the difference was statistically significant(P<0.05). Correlation analysis results showed that RTS score,D-lactic acid,DAO level were positively correlated with APACHEⅡscore(P<0.05). The ROC curve analysis results showed that the area under curve(AUC),sensitivity,and specificity of the three combined examinations in assessing the prognosis of patients with traumatic fractures and shock were significantly higher than those of a single test. Conclusion The RTS score of patients with traumatic fracture and shock significantly increases,and the levels of D-lactate and DAO are abnormally expressed,and have some correlation with APACHEⅡ,which can be used as auxiliar

关 键 词：RTS评分 D-乳酸 二胺氧化酶 创伤性骨折 

分 类 号：R683[医药卫生—骨科学]