普通超声与超声造影在乳腺癌诊断及新辅助化疗疗效评估中的价值分析  

Value analysis of conventional ultrasonography and contrast-enhanced ultrasonography in the diagnosis of breast cancer and evaluation of the efficacy of neoadjuvant chemotherapy

作　　者：杨爽[1] 刘宏武[1] 尹丽[1] 胡艳[1] YANG Shuang;LIU Hongwu;YIN Li(Department of Ultrasound,Zhongshan Hospital Affiliated to Dalian University,Dalian 116001,China)

机构地区：[1]大连大学附属中山医院超声科,116001

出　　处：《中国实用医药》2022年第5期83-85,共3页China Practical Medicine

摘　　要：目的 比较分析普通超声与超声造影在乳腺癌诊断及新辅助化疗疗效评估中的价值。方法 116例乳腺癌患者,分别采取普通超声检查和超声造影检查进行诊断。比较两种检查方式的诊断阳性率、化疗前后的病灶大小检测结果 ,比较化疗前后超声造影检测指标。结果 超声造影检查的乳腺癌阳性检出率94.83%(110/116)显著高于普通超声检查的62.07%(72/116),差异有统计学意义(P<0.05)。化疗后,超声造影检查的病灶最大直径(11.12±2.19)mm、上下径(19.37±5.31)mm均显著小于普通超声检查的(15.48±2.27)、(21.87±5.44)mm,差异均有统计学意义(P<0.05)。化疗后,超声造影检测的上升时间(RT)、上升斜率(WIS)、达峰时间(TTP)与化疗前比较,差异无统计学意义(P>0.05);化疗后,超声造影检测的曲线下面积(AUC)、峰值强度(PI)均显著低于化疗前,差异均有统计学意义(P<0.05)。结论 超声造影检查对乳腺癌患者的诊断阳性率明显高于普通超声,超声造影在乳腺癌诊断及新辅助化疗疗效评估中优势显著。Objective To compare and analyze the value of conventional ultrasonography and contrast-enhanced ultrasonography in the diagnosis of breast cancer and the evaluation of the efficacy of neoadjuvant chemotherapy.Methods 116 breast cancer patients were diagnosed by conventional ultrasonography and contrast-enhanced ultrasonography.The positive detection rate,lesion size and contrast-enhanced ultrasound detection indexes before and after chemotherapy were compared between the two examination methods.Results The positive detection rate of breast cancer of contrast-enhanced ultrasonography was 94.83%(110/116),which was significantly higher than 62.07%(72/116)of conventional ultrasonography,and the difference was statistically significant(P<0.05).After chemotherapy,the maximum diameter(11.12±2.19)mm and the upper and lower diameters(19.37±5.31)mm in contrast-enhanced ultrasonography were significantly less than(15.48±2.27)and(21.87±5.44)mm in conventional ultrasonography,and the differences were statistically significant(P<0.05).After chemotherapy,the differences in rise time(RT),wash in slope(WIS)and time to peak(TTP)detected by contrast-enhanced ultrasonography were not statistically significant when compared with those before chemotherapy(P>0.05).After chemotherapy,the area under the curve(AUC)and peak intensity(PI)detected by contrast-enhanced ultrasound were significantly lower than those before chemotherapy,and the differences were statistically significant(P<0.05).Conclusion The positive rate of contrast-enhanced ultrasonography in breast cancer patients is significantly higher than that of conventional ultrasonography,and contrast-enhanced ultrasonography has significant advantages in the diagnosis of breast cancer and evaluation of the efficacy of neoadjuvant chemotherapy.

关 键 词：普通超声 超声造影 乳腺癌 诊断 新辅助化疗 疗效评估 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]