中国老年人代谢综合征患病率META分析  

Prevalence of metabolic syndrome in Chinese elderly:a META-analysis

作　　者：李燕萍 周裕婧[1] 朱士胜 赵晓龙 LI Yan-ping;ZHOU Yu-jing;ZHU Shi-sheng;ZHAO Xiao-long(Chongqing Medical and Phamaceutical College,Chongqing 401331)

机构地区：[1]重庆医药高等专科学校,重庆401331 [2]解放军第956医院

出　　处：《现代预防医学》2022年第5期913-917,共5页Modern Preventive Medicine

基　　金：重庆市教委科技研究(KJQN201902804);重庆市教育委员会十三五规划课题(2016-GX-174)。

摘　　要：目的通过Meta分析描述我国老年人代谢综合征(Metabolic syndrome,MS)患病率水平,为老年人MS的防控提供科学依据。方法系统检索2005—2021年在中国期刊全文数据库(CNKI)、万方数据资源系统(Wanfang database)、维普数据库(VIP)及PubMed、Embase、Cochrane library中收录的有关中国老年人MS患病率研究的文献。采用美国卫生保健质量和研究机构(Agency for Healthcare Research and Quality,AHRQ)编制的横断面研究质量评价量表对入选文献进行文献质量评价。采用Stata 16.0软件进行数据合并估算患病率,并对性别、地区差异、发表时间、年龄因素进行亚组分析,采用Egger检验判断发表偏倚,通过排除其中任意一篇文献对合并效应值的影响来进行敏感性分析。结果共纳入21篇研究文献,共77190名老年人,中国老年人MS的合并患病率为23.9%(95%CI:21.8%~26.1%);亚组分析显示,老年男性的合并患病率为21.6%(95%CI:19.5%~23.8%),老年女性的合并患病率为26.1%(95%CI:23.6%~28.6%),老年女性的MS的合并患病率明显高于男性(P=0.008);而以地域,年龄以及发表年度作为亚组划分,各组老年人MS的合并患病率无明显差异。结论近20年来,我国老年人MS患病率无明显变化,应注重对老年女性MS的预防。Objective To describe the prevalence of metabolic syndrome in the Chinese elderly through META-analysis,and to provide scientific basis for the prevention and control of metabolic syndrome in the elderly.Methods Literatures about the prevalence of metabolic syndrome in the elderly in China from 2005 to 2021 were searched in CNKI,Wanfang Database,VIP,PubMed,EMBASE and Cochrane Library.The cross-sectional study quality assessment scale developed by the Agency for Healthcare Research and Quality(AHRQ)was used to evaluate the literature quality of the selected articles.Stata 16.0 software was used to estimate the prevalence rate,and the factors of gender,regional differences,publication time and age were analyzed by subgroup analysis.Egger test was used to test the publication bias,and the sensitivity analysis was conducted by excluding the influence of any literature on the combined effect value.Results A total of 21 studies involving 77190 elderly people were included.The prevalence of metabolic syndrome in Chinese elderly was 23.9%(95%CI:21.8%-26.1%).Subgroup analysis showed that the prevalence of MS in elderly men was 21.6%,and that in elderly women was 26.1%.The prevalence of MS in elderly women was significantly higher than that in men(P<0.01).However,there was no significant difference in the prevalence of metabolic syndrome among the three sub-groups by region,age and publication year.Conclusion In recent 10 years,the prevalence of metabolic syndrome in the elderly has not changed significantly in China.We should pay attention to the prevention of metabolic syndrome in elderly women.

关 键 词：代谢综合征 老年人 患病率 META分析 

分 类 号：R161.7[医药卫生—公共卫生与预防医学] R589