三种骨密度体模DXA一致性测试  

Consistency Test of Three Bone Mineral Density Phantoms Under Dual Energy X-Ray Absorptiometry

作　　者：方帅[1] 顾加雨 夏勋荣 FANG Shuai;GU Jiayu;XIA Xunrong(Institute of Medical,Jiangsu Institute of Metrology,Nanjing Jiangsu 210023,China)

机构地区：[1]江苏省计量科学研究院医学所,江苏南京210023

出　　处：《中国医疗设备》2022年第3期9-12,共4页China Medical Devices

基　　金：国家重点研发计划(2016YFF0201003)。

摘　　要：目的比较华科QC-2、欧洲QRM-ESP和美国BFP-Cirs026三种骨密度体模在双能X射线(Dual Energy X-ray Absorptiometry,DXA)骨密度仪上测试的通用性、适应性和测量结果的一致性。方法选用GE-Lunar和Hologic-Discovery两种DXA分别对这三种体模的模拟椎骨进行测试,对骨密度值进行比较分析,用最小二乘法拟合线性回归方程,校正测量结果,并分析其相关性。结果三种体模分别被GE和Hologic DXA测量的相对误差都很大(-9.1%~31.3%),经线性回归方程校正后,校正值与相应体模的标称值相对误差范围在-2.5%~5.5%,测量结果和相应的体模标称值具有高度的线性相关性,相关系数r>0.99。结论三种体模都可用于DXA的检定和试验,其测量结果具有很好的一致性,其中ESP体模适应性最佳。Objective To compare the generality,adaptability,and consistency of bone mineral density(BMD)phantoms named Huake QC-2,QRM-ESP and BFP-Cirs026 under dual energy X-ray absorptiometry(DXA).Methods GE-Lunar and Hologic-Discovery DXA were used to test the simulated vertebrae of the three phantom respectively,and the measurement results of BMD were compared and analyzed.The least square method was used to fit the linear regression equation,the measurement results were corrected and the correlation was analyzed.Results The relative errors of the three phantoms measured by GE and Hologic DXA were very large(-9.1%-31.3%)respectively.After correction by linear regression equation,the relative errors range between the corrected values and the nominal values of the corresponding phantom was from-2.5%to 5.5%.There was a high linear correlation between the measurement results and the corresponding phantom nominal values,and the correlation coefficient r>0.99.Conclusion The three kinds of phantom can be used for DXA verification and test,and the measurement results have good consistency,among which the ESP phantom has the best adaptability.

关 键 词：骨矿密度 骨密度体模 DXA密度仪 羟磷酸钙 线性相关 

分 类 号：R194[医药卫生—卫生事业管理] TH789[医药卫生—公共卫生与预防医学]