补肾养肝活血汤辅助治疗寻常痤疮的疗效分析  

Analysis of the Curative Effect of Bushen Yanggan Huoxue Decoction in the Adjuvant Treatment of Acne Vulgaris

作　　者：龙惠[1] 何伟强[1] 孙昌洁 张玉艳[1] 陈嘉 LONG Hui;HE Wei-qiang;SUN Chang-jie;ZHANG Yu-yan;CHEN Jia(Guangzhou Institute of Dermatology Prevention and Treatment,Guangdong Guangzhou 510095)

机构地区：[1]广州市皮肤病防治所,广东广州510095

出　　处：《深圳中西医结合杂志》2021年第24期53-55,共3页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的:分析补肾养肝活血汤辅助治疗寻常痤疮的疗效。方法:选取广州市皮肤病防治所2019年5月至2021年3月期间收治的121例寻常痤疮患者,按照随机数字表法分为对照组(60例)与观察组(61例)。对照组给予四环素片+维生素B6治疗,观察组在对照组基础上予以补肾养肝活血汤治疗。观察两组患者临床疗效、皮肤生理指标以及面部恢复情况。结果:观察组患者治疗总有效率为91.80%,高于对照组的78.34%,差异具有统计学意义(P<0.05)。治疗后观察组患者的经表皮失水率(TEWL)、红斑指数(EI)、皮肤颜色指数黑素指数(MI)低于对照组,皮肤弹性指数(R2)高于对照组,差异具有统计学意义(P<0.05)。治疗后观察组患者的毛孔、棕色斑、面部红色区得分均低于对照组,差异具有统计学意义(P<0.05)。结论:补肾养肝活血汤辅助治疗寻常痤疮通过减轻或消除面部皮损,改善皮肤生理指标,进而促进面部恢复。Objective To analyze the efficacy of Bushen Yanggan Huoxue Decoction in the adjuvant treatment of acne vulgaris.Methods A total of 121 patients with acne vulgaris admitted to Guangzhou Institute of Dermatology from May 2019 to March 2021 were divided into a control group(60 cases)and an observation group(61 cases)according to a random number table.The control group was treated with tetracycline tablets combined with vitamin B6,and the observation group was treated with Bushen Yanggan Huoxue Decoction on the basis of the control group.The clinical efficacy,skin physiological indicators and facial recovery of the two groups of patients were observed.Results The total effective rate of the observation group was 91.80%,which was higher than 78.34% of the control group,and the difference was statistically significant(P<0.05).After treatment,the rate of trans-epidermal water loss(TEWL),erythema index(EI),skin color index melanin index(MI),of the observation group were lower than those of the control group and the skin elasticity index(R2)was higher than that of the control group,the differences were statistically significant(P<0.05).After treatment,the scores of pores,brown spots and facial red areas in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Bushen Yanggan Huoxue Decoction in the adjuvant treatment of acne vulgaris can reduce or eliminate facial skin lesions,improve skin physiological indexes,and then promote facial recovery.

关 键 词：寻常痤疮 补肾养肝活血汤 四环素片 维生素B6 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]