我院注射用质子泵抑制剂临床使用合理性评价  

Rational Evaluation of Clinical Application of Proton Pump Inhibitors for Injection in our Hospital

作　　者：谢丽珊[1] 赖鹏辉 林建红[1] 刘全芳 林素珍[1] XIE Li-shan;LAI Peng-hui;LIN Jian-hong;LIU Quan-fang;LIN Su-zhen(Dept.of Pharmacy,the Second Hospital of Longyan,Longyan 364000,China)

机构地区：[1]龙岩市第二医院药剂科,福建龙岩364000

出　　处：《海峡药学》2022年第2期160-163,共4页Strait Pharmaceutical Journal

摘　　要：目的了解我院注射用质子泵抑制剂(PPI)的临床使用情况。方法回顾性调查2020年10月份使用注射用PPI制剂病历1316份,随机抽取外科系统100份病历进行预防性应用的合理性评价。结果注射用雷贝拉唑钠使用量最多,占比达73.71%,其次为注射用艾司奥美拉唑钠(16.41%)、注射用奥美拉唑钠(7.22%)、注射用兰索拉唑(2.66%)(我院无注射用泮托拉唑)。不合理率平均83%,使用大部分存在不合理现象。不合理项目主要为给药途径不适宜(32.93%)、药品选择不适宜(31.73%)、无适应证用药(24.50%)及疗程偏长(10.84%)。结论注射用质子泵抑制剂预防性应用的合理性可以进一步优化。OBJECTIVE To understand the clinical use of the proton pump inhibitors for Injection(PPI)in our hospital.METHODS A retrospective survey of 1316 medical records using PPI preparations for injection in October 2020 was conducted,and 100 medical records from the surgical system were randomly selected to evaluate the rationality of preventive application.RESULTS Rabeprazole Sodium for Injection was used the most,accounting for 73.71%,followed by Esomeprazole Sodium for Injection(16.41%),Omeprazole Sodium for Injection(7.22%),Lansoprazole for Injection(2.66%)(there is no Pantoprazole for Injection in our hospital).The unreasonable rate is 83%on average,and most of them are unreasonable.The main errors included inappropriate route of administration(32.93%),inappropriate choice of drugs(31.73%),no indication drug use(24.50%)and long treatment course(10.84%).CONCLUSION The rationality of the preventive application of proton pump inhibitors for injection can be further optimized.

关 键 词：注射用质子泵抑制剂 应激性黏膜病变(SRMD) 合理用药 

分 类 号：R969.4[医药卫生—药理学]