寻常型间质性肺炎与非特异性间质性肺炎的临床特点及HRCT表现对比分析  

Comparative Analysis of the Clinical Features and CT Findings of Usual Interstitial Pneumonia and Nonspecific Interstitial Pneumonia

作　　者：曾显荣 弋春燕 刘庆玲 黄社磊 黄钦熊 王娟娟 马捷 ZENG Xian-rong;YI Chun-yan;LIU Qing-ling;HUANG She-lei;HUANG Qin-xiong;WANG Juan-juan;MA Jie(Department of Radiology,Shenzhen People's Hospital(the Second Clinical Medical College,Jinan University,the First Affiliated Hospital,Southern University of Science and Technology),Shenzhen 518020,Guangdong Province,China)

机构地区：[1]深圳市人民医院(暨南大学第二临床学院,南方科技大学第一附属医院)放射科,广东深圳518020

出　　处：《中国CT和MRI杂志》2022年第4期39-42,共4页Chinese Journal of CT and MRI

基　　金：深圳市科技研发资金(JCYJ20180305164740612)。

摘　　要：目的对比分析寻常型间质性肺炎(UIP)和非特异性间质性肺炎(NSIP)的临床特点及HRCT表现,探讨其在UIP和NSIP鉴别诊断中的价值。方法回顾性分析我院2010年1月至2019年12月经临床-影像-病理综合诊治的58例UIP和55例NSIP患者的临床特点、HRCT表现及与肺气肿亚型的相关性。结果UIP发病年龄高于NSIP,UIP以男性患者为主,NSIP以女性为主;两者发病的年龄及性别差异具有统计学意义(P<0.01)。两者临床症状无明显差异(P=0.40),UIP的吸烟者比例明显高于NSIP(P<0.01)。两者在合并肺气肿亚型(PSE、CLE)及不伴肺气肿的差异具有统计学意义(P<0.01),而在合并PSE+CLE中的差异无统计学意义(P=0.08)。在UIP与NSIP的其它合并症(肺动脉高压、肺癌、纵隔淋巴结肿大、胸腔积液、心包积液等)的差异均无统计学意义(P>0.05)。结论HRCT在UIP与NSIP鉴别诊断中具有显著的优势。肺气肿亚型在UIP与NSIP的鉴别诊断中具有重要意义,且两者与发病平均年龄及性别密切相关。Objective To comparative analyze the clinical features and HRCT findings of usual interstitial pneumonia(UIP)and nonspecific interstitial pneumonia(NSIP),and to explore their value in differential diagnosis of UIP and NSIP.Methods The clinical features,HRCT findings and correlation with emphysema of 58 UIP and 55 NSIP patients diagnosed by clinical-radiological-Pathological comprehensive analysis in our hospital from January 2010 to December 2019 were analyzed retrospectively.Results The age of onset of UIP was higher than NSIP,UIP patients were mainly male,while NSIP patients were mainly female,and the difference was statistically significant(P<0.01).There was no significant difference in clinical symptoms between the two groups(P=0.40).The smoking rate of UIP was higher than that of NSIP(P<0.01).The difference of emphysema subtypes(PSE,CLE)and without emphysema between the two groups was statistically significant(P<0.01),except PSE+CLE(P=0.08).There were no significant differences between UIP and NSIP in other complications(pulmonary hypertension,lung cancer,mediastinal lymph node enlargement,pleural effusion,pericardial effusion,etc.,P>0.05).Conclusion HRCT has significant advantages in differential diagnosis between UIP and NSIP.The subtypes of emphysema are significant for differential diagnosis of UIP and NSIP,and are closely related to gender and the age of onset.

关 键 词：肺炎 肺气肿 体层摄影术 X线计算机 

分 类 号：R445.2[医药卫生—影像医学与核医学] R563.1[医药卫生—诊断学]