COPD合并肺气肿患者MSCT肺容积百分比与常规肺功能的相关性研究  

Correlation between the Percentage of MSCT Lung Volume and Conventional Lung Function in COPD Patients with Emphysema

作　　者：胡政乾 耿雪 朱红伟[1] 周志强[1] 郝继伟[1] HU Zheng-qian;GENG Xue;ZHU Hong-wei;ZHOU Zhi-qiang;HAO Ji-wei(CT Room,the No.2 Hospital of Baoding,Baoding 071000,Hebei Province,China)

机构地区：[1]保定市第二医院CT室,河北保定071000

出　　处：《中国CT和MRI杂志》2022年第4期48-50,共3页Chinese Journal of CT and MRI

基　　金：河北省医学科学研究重点课题计划(20160105)。

摘　　要：目的分析COPD合并肺气肿患者MSCT肺容积百分比与常规肺功能的相关性。方法回顾性收集2017年9月至2019年9月在本院收治的52例COPD合并肺气肿患者的临床资料。另选取同期在本院治疗的单纯COPD患者61例。观察患者所得图像,对比不同COPD患者肺功能指标差异以及不同程度废气中患者LAV%差异,并分析LAV%与肺功能指标相关性。结果COPD合并肺气肿组患者FEV;/FVC、FEV;%、DLCO%低于单纯COPD患者,RV/TLC高于单纯COPD患者(P<0.05);轻度肺气肿患者30例,重度肺气肿患者22例。轻度肺气肿患者全肺、右肺、左肺等各个肺叶LAV%值均明显低于重度肺气肿患者(P<0.05);全肺、右下肺、左肺、左下肺LAV%与FEV;/FVC为负相关(P<0.05),右肺上叶、中叶、左肺上叶与FEV;/FVC无相关性(P>0.05);全肺、右肺(上、中、下)、左肺(上、下)LAV%与DLCO%为负相关(P<0.05),肺各部LAV%与FEV;%、RV/TLC无相关性(P<0.05)。结论COPD合并肺气肿患者MSCT肺容积百分比与FEV;/FVC、DLCO%存在相关性,可为临床诊断、治疗、病情监测提供参考依据。Objective To analyze the correlation between the percentage of MSCT lung volume and conventional lung function in COPD patients with emphysema.Methods The clinical data of 52 patients with COPD and emphysema admitted in our hospital from September 2017 to September 2019 were collected retrospectively.In addition,61 patients with COPD treated in our hospital during the same period were selected.The images of the patients were observed.The differences in lung function indexes of patients with COPD and the differences in LAV%of patients with different degrees of emphysema were compared,and the correlation between LAV%and lung function indexes was analyzed.Results FEV;/FVC,FEV;%,and DLCO%in the patients with COPD combined with emphysema were lower than those in COPD patients,and RV/TLC was higher than those in COPD patients(P<0.05).There were 30 patients with mild emphysema and 22 patients with severe emphysema.The LAV%values in the whole lung,right lung,left lung and other lung lobes of patients with mild emphysema were significantly lower than those of patients with severe emphysema(P<0.05).The LAV%in the whole lung,lower right lung,left lung,and lower left lung were negatively correlated with FEV;/FVC(P<0.05),and the LAV%in the right upper lobe,middle lobe,and left upper lobe were not correlated with FEV;/FVC(P>0.05).The LAV%of the whole lung,right lung(upper,middle,and lower)and left lung(upper and lower)were negatively correlated with DLCO%(P<0.05),and LAV%of each lung had no correlation with FEV;%and RV/TLC(P<0.05).Conclusion The percentage of MSCT lung volume in patients with COPD and emphysema is correlated with FEV;/FVC and DLCO%,which can provide reference for clinical diagnosis,treatment and disease monitoring.

关 键 词：COPD 合并肺气肿 MSCT 肺容积百分比 常规肺功能 

分 类 号：R445.3[医药卫生—影像医学与核医学] R563.3[医药卫生—诊断学]