基于表面等离子体共振的光子晶体光纤癌胚抗原浓度传感器  

Photonic crystal fiber carcinoembryonic antigen concentration sensor based on surface plasmon resonance

作　　者：李青枫 姜如珊 张汇一 施伟华 LI Qingfeng;JIANG Rushan;ZHANG Huiyi;SHI Weihua(College of Electronic and Optical Engineering&College of Microelectronics,Nanjing University of Posts and Telecommunications,Nanjing 210023,China)

机构地区：[1]南京邮电大学电子与光学工程学院、微电子学院,南京210023

出　　处：《光通信技术》2022年第2期75-78,共4页Optical Communication Technology

基　　金：国家自然科学基金项目(61571237)资助;江苏省重点(国家级)大学生创新训练计划项目(SZDG2019013)资助。

摘　　要：为了提高生物参量检测的灵敏度和避免电磁干扰,提出一种基于表面等离子共振的光子晶体光纤传感器应用于癌胚抗原(CEA)溶液的检测。该传感器采用不同直径空气孔进行三层排列的结构,将金薄膜作为金属层镀在纤芯表面,并在金薄膜和待测CEA溶液间增加一层基于核酸适配子的特异性适配层,采用全矢量有限元法对该传感器进行数值模拟与仿真。仿真结果表明:在折射率1.33~1.41范围内,该传感器具有明显的表面等离子体共振效应,灵敏度可达10000 nm/RIU,线性度为0.94919。In order to improve the sensitivity of biological parameter detection and avoid electromagnetic interference,a photonic crystal fiber sensor based on surface plasmon resonance is proposed for the detection of carcinoembryonic antigen(CEA) solution.The sensor adopts a three-layer arrangement structure of air holes with different diameters.The gold film is plated on the surface of the fiber core as a metal layer,and a specific adaptation layer based on nucleic acid aptamer is added between the gold film and the CEA solution.The full vector finite element method is used to numerical simulate and emulate the sensor.The simulation results show that the sensor has obvious surface plasmon resonance effect in the refractive index range of 1.33~1.41.The sensitivity of the structure can reach 10000 nm/RIU and the linearity is 0.94919.

关 键 词：癌胚抗原 折射率传感 光子晶体光纤 灵敏度 线性度 

分 类 号：TN29[电子电信—物理电子学] O436[机械工程—光学工程]