艾炷灸足三里治疗脾胃虚弱型非小细胞肺癌靶向药物相关性腹泻的疗效观察  

Efficacy Observation of Moxa-cone Moxibustion at Zusanli(ST36)for Diarrhea of Spleen-stomach Deficiency Pattern Associated with Targeted Drugs in Treating Non-small-cell Lung Cancer

作　　者：李镜 戎姣 杨玉平[1] 李海玲 LI Jing;RONG Jiao;YANG Yuping;LI Hailing(Weifang Hospital of Traditional Chinese Medicine,Weifang 261000,China;Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]潍坊市中医院,潍坊261000 [2]山东中医药大学,济南250014

出　　处：《上海针灸杂志》2022年第3期238-242,共5页Shanghai Journal of Acupuncture and Moxibustion

基　　金：齐鲁医派中医药特色技术整理推广项目;潍坊市中医药科学技术研究项目(NO.084)。

摘　　要：目的观察艾炷灸足三里治疗脾胃虚弱型非小细胞肺癌靶向药物相关性腹泻的临床疗效。方法将100例脾胃虚弱型非小细胞肺癌靶向药物相关性腹泻患者随机分为治疗组和对照组,每组50例。治疗组采用艾炷灸足三里治疗,对照组采用口服蒙脱石散治疗。观察两组治疗前后中医证候积分的变化,并比较两组的临床疗效。结果治疗组总有效率为88.0%,对照组总有效率为70.0%,两组比较差异具有统计学意义(P<0.05)。两组治疗后中医证候积分与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗后腹胀腹痛、肠鸣、脘腹痞满积分与对照组比较,差异无统计学意义(P>0.05),大便泄泻、食欲不振、倦怠乏力、神疲懒言及症状总积分与对照组比较,差异具有统计学意义(P<0.05)。结论艾炷灸足三里治疗脾胃虚弱型非小细胞肺癌靶向药物相关性腹泻具有较好的疗效。Objective To observe the clinical efficacy of moxa-cone moxibustion at Zusanli(ST36)in treating diarrhea of spleen-stomach deficiency pattern due to targeted drugs for non-small-cell lung cancer(NSCLC).Method One hundred patients with diarrhea of spleen-stomach deficiency pattern due to targeted drugs for NSCLC were randomized into a treatment group and a control group,with 50 cases in each group.The treatment group was given moxa-cone moxibustion at Zusanli.The control group was treated with Montmorillonite powder.Before and after the treatment,the traditional Chinese medicine(TCM)symptom score was observed for both groups.The clinical efficacy was also compared.Result The total effective rate was 88.0%in the treatment group versus 70.0%in the control group,and the between-group difference was statistically significant(P<0.05).The TCM symptom score markedly changed after the intervention in both groups(P<0.05).After the treatment,there were no significant differences in the scores of abdominal bloating and pain,bowel sounds,or stomach fullness between the two groups(P>0.05),while the between-group differences in the scores of loose stools,poor appetite,lassitude,and low spirit and the total symptom score were statistically significant(P<0.05).Conclusion Moxa-cone moxibustion at Zusanli can produce satisfactory efficacy in treating diarrhea of spleen-stomach deficiency pattern caused by targeted drugs for NSCLC.

关 键 词：灸法 艾炷灸 穴 足三里 腹泻 癌 非小细胞肺 药物相关的副作用及不良反应 

分 类 号：R246.5[医药卫生—针灸推拿学]