新疆乌鲁木齐女性绝经状态与血脂变化相关性及影响因素  

Correlation and Influential Factors between Menopausal Status and Blood Lipid Changes in Women in Urumqi of Xinjiang

作　　者：加孜热亚·再依拿提 罗蕴芝[1] 李素丽[1] 沙依拉·海米提 热那姑丽·艾克拜尔 张玉媛 王新玲[1] Jiazireya Zaiyinati;Luo Yunzhi;Li Suli;Shayila Hamiti;Renaguli Aikebaier;Zhang Yuyuan;Wang Xinling(Department of Endocrinology,People's Hospital of Xinjiang Uygur Autonomous Region,Unumqi 830001)

机构地区：[1]新疆维吾尔自治区人民医院内分泌科,乌鲁木齐830001

出　　处：《国际老年医学杂志》2022年第2期149-153,共5页International Journal of Geriatrics

基　　金：新疆维吾尔自治区自然科学基金(2017D01C105)。

摘　　要：目的通过调查围绝经期及绝经后女性血脂水平、腰围、体质指数(BMI)水平,探讨围绝经期及绝经后女性血脂水平的变化特点及其影响因素,同时探讨血脂功能筛查的意义。方法选取乌鲁木齐城区2个社区2018年4~6月的常驻人群作为研究对象,采用横断面整群随机抽样方法进行抽样,共纳入620例,根据月经情况分为月经规律组(284例)、围绝经期组(117例)、绝经后组(219例),比较三组的血脂水平、腰围、BMI,分析三组女性血脂异常及肥胖、腹型肥胖患病情况。结果围绝经期组三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、体质量分类、腹型肥胖与其他两组比较差异均无统计学意义(P>0.05);围绝经期组总胆固醇(TC)低于绝经后组,差异有统计学意义(P<0.05)。围绝经期组和绝经后组的血脂异常患病率及高TC血症、高TG血症、高LDL-C血症患病率均高于月经规律组(P<0.05),围绝经期组和绝经后组这些指标比较,差异均无统计学意义(P>0.05)。logistic回归分析显示,围绝经期、绝经后期腰围均为患血脂异常的危险因素(P<0.05)。结论新疆地区围绝经期组的血脂异常患病率高于月经规律人群,和绝经后人群无差异,应该从围绝经期时期关注女性的血脂水平,早期进行有效干预,减少血脂异常的发生。Objective To explore the changes and influential factors of blood lipid levels in perimenopausal and postmenopausal women by measuring blood lipid levels, waist circumference and body mass index(BMI),and discusse the significance of blood lipid profile screening.Methods The resident population in two communities in Urumqi from April 2018 to June 2018 was selected as subjects, and 620 cases were included by cross-sectional study.They were divided into regular menstruation group(284 cases),perimenopause group(117 cases),and postmenopause group(219 cases) according to the menstrual status.The blood lipid levels, waist circumference, and BMI were compared between the groups.The prevalence of dyslipidemia, obesity and abdominal obesity in the three groups were analyzed.Results There were no significant differences in the levels of triglyceride(TG),low density lipoprotein cholesterol(LDL-C),BMI classification and the prevalence of abdominal obesity between perimenopause group and the other two groups(P>0.05).The level of total cholesterol(TC) in perimenopause group was significantly lower than that in postmenopause group(P<0.05).The prevalences of dyslipidemia, hypercholesterolemia, hypertriglyceridemia and high LDL-C level were higher in perimenopause and postmenopause groups than those in regular menstruation group(P<0.05),while there were no significant differences between perimenopause group and postmenopause group(P>0.05).Logistic regression analysis showed that perimenopause, postmenopause and waist circumference were risk factors for dyslipidemia(P<0.05).Conclusion The prevalence of dyslipidemia in perimenopausal women in Xinjiang is higher than that in regular menstrual population, which is similar to that in postmenopausal population.We should pay attention to the blood lipid levels in women in perimenopause period, and carry out effective early intervention to reduce the occurrence of dyslipidemia.

关 键 词：围绝经期 绝经后 血脂 肥胖 新疆 

分 类 号：R711.75[医药卫生—妇产科学]