大学生家族性原发性遗尿症现状调查  

Survey of familial primary nocturnal enuresis in university students

作　　者：文建军[1] 胡绘杰 罗艳艳[3] 梁钰 张振威 王庆伟[6] 姚武[7] 宋翠萍[4] 窦启锋[5] 文建国[6] WEN Jianjun;HU Huijie;LUO Yanyan;LIANG Yu;ZHANG Zhenwei;WANG Qingwei;YAO Wu;SONG Cuiping;DOU Qifeng;WEN Jianguo(Department of Emergency,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052;Department of Humanities,School of Nursing,Sanquan College,Xinxiang Medical University,Xinxiang,Henan 453003;Department of Surgery,Nursing School,Xinxiang Medical University,Xinxiang,Henan 453003;Department of Pediatric Surgery,the First Affiliated Hospital,Xinxiang Medical University,Weihui,Henan 453100;Department of Urology,the First Affiliated Hospital,Xinxiang Medical University,Weihui,Henan 453003;Henan Joint International Pediatric Urodynamic Laboratory,the First Affiliated Hospital,Zhengzhou University,Zhengzhou 450052;Department of Labor Hygiene,College of Public Health,Zhengzhou University,Zhengzhou 450001)

机构地区：[1]郑州大学第一附属医院急诊科,郑州450052 [2]新乡医学院三全学院护理学院人文教研室,河南新乡453003 [3]新乡医学院护理学院外科教研室,河南新乡453003 [4]新乡医学院第一附属医院小儿外科,河南卫辉453100 [5]新乡医学院第一附属医院泌尿外科,河南卫辉453003 [6]郑州大学第一附属医院河南省小儿尿动力国际联合实验室,郑州450052 [7]郑州大学公共卫生学院劳动卫生学教研室,郑州450001

出　　处：《郑州大学学报（医学版）》2022年第2期258-261,共4页Journal of Zhengzhou University(Medical Sciences)

基　　金：国家自然科学基金项目(U1904208);河南省医学科技攻关计划省部共建项目(SBGJ2018059)。

摘　　要：目的:研究大学生家族性原发性遗尿(PNE)的现状。方法:采用匿名问卷调查的方式对河南省3所大学的22500名在校大学生(17~21岁)进行PNE流行病学调查。调查患者的PNE家族史,比较有无家族史患者PNE下尿路症状的差异。结果:共回收有效问卷20345份,其中PNE患者239例(1.17%),男88例,女151例。有家族史者81例,其中41个(50.62%)家系符合常染色体显性遗传,22个(27.16%)家系符合常染色体隐性遗传。有家族史的PNE大学生患者泌尿系感染,严重PNE和尿频、尿急、尿失禁的发生率均高于无家族史患者(P<0.05)。结论:大学生家族性PNE多见,有多种遗传方式。有家族史的PNE大学生患者更易出现并发症,应尽早干预治疗。Aim:To investigate the status of familial primary nocturnal enuresis(PNE)in university students.Methods:An epidemiological survey of PNE was carried out in 22500 university students(aged 17-21 years)from 3 universities in Henan Province by anonymous questionnaire.A total of 239 PNE patients were found.Their family history were collected and the difference of lower urinary tract symptoms were compared between the cases with and without family history.Results:A total of 20345 questionnaires qualified for statistical analysis.The prevalence of PNE was 1.17%,including 88 males and 151 females.There were 81 cases with family history,out of which 41 families(50.62%)were autosomal dominant inheritance and 22 families(27.16%)were autosomal recessive inheritance.The incidence of urinary tract infection,severe PNE,frequent urination,urgent urination and urinary incontinence in cases with family history of PNE were higher than those without family history(P<0.05).Conclusion:Familial PNE is common in university students and multiple genetic modes coexist.More common of daytime lower urinary tract symptoms indicating early medical intervention should be considered in university students with familial PNE.

关 键 词：原发性遗尿 下尿路症状 家族史 大学生 

分 类 号：R691[医药卫生—泌尿科学]