心血管病高危人群静息心率与颈动脉斑块发生的关联研究  

Relationship between resting heart rate and risk of carotid plaque in high-risk population of cardiovascular disease

作　　者：吴玲玲 刘付东[1] 郑春早 梁季[1] 祁朝霞 覃玉[2] 周羚[2] 苏健[2] 崔岚[2] 杜文聪[2] 周金意[2] 张名贵 WU Ling-ling;LIU Fu-dong;ZHENG Chun-zao;LIANG Ji;Qi ZHAO-xiao;QIN Yu;ZHOU Ling;SU Jian;CUI Lan;DU Wen-cong;ZHOU Jin-yi;ZHANG Ming-gui(Yancheng Municipal Center for Disease Control and Prevention,Jiangsu Yancheng 224100,China;不详)

机构地区：[1]盐城市疾病预防控制中心,江苏盐城224100 [2]江苏省疾病预防控制中心 [3]上海市上农医院

出　　处：《江苏预防医学》2022年第1期29-32,共4页Jiangsu Journal of Preventive Medicine

基　　金：国家重大公共卫生项目(财社[2015]82号)。

摘　　要：目的探讨江苏省心血管病高危人群静息心率与颈动脉斑块的关系。方法 2015—2016年在江苏省6个项目点对11 362名心血管病高危人群进行问卷调查、体格测量和颈动脉超声检查,按静息心率测量值分为≤60、61~70、71~80、81~90、≥91次/min共5组(Q1~Q5),采用非条件logistic回归模型分析静息心率与颈动脉斑块的关联。结果 11 362名心血管病高危人群颈动脉斑块、内膜增厚、颈动脉狭窄检出率分别为36.70%、15.68%、3.32%。与Q1组相比,≥60岁人群的Q5组颈动脉斑块发生风险明显增加(OR=1.48,95%CI:1.14~1.92,P<0.05),年龄<60岁人群静息心率与颈动脉斑块发生风险无统计学关联(P值均>0.05);分性别分析,男性Q5组颈动脉斑块发生风险明显增加(OR=1.58,95%CI:1.16~2.15),而女性静息心率与颈动脉斑块发生风险未见统计学关联(P值均>0.05)。结论江苏省心血管病高危人群颈动脉异常检出率较高,高静息心率的高龄男性人群发生颈动脉斑块风险较高。Objective To explore the relationship between resting heart rate and carotid plaque in high risk of cardiovascular disease population in Jiangsu Province.Methods A total of 11 362 high-risk subjects of cardiovascular diseases from 6 sites of Jiangsu Province from 2015 to 2016 were subjected to questionnaire interview,physical examination and carotid artery ultrasound examination.The participants were categorized into 5 groups according to the resting heart rate of ≤60,61-70,71-80,81-90 and≥91 beats/min(Q1-Q5).The relationship between resting heart rate and carotid plaque was analyzed by non-conditional logistic regression model.Results The detection rates of carotid plaque,carotid intima-media thickening and carotid stenosis in the high-risk population of cardiovascular disease were 36.70%,15.68%and 3.32%,respectively.Compared to Q1 group,the subjects older than 60 years in Q5 group had higher risk of carotid plaque(OR=1.48,95%CI:1.14-1.92,P<0.05),the subjects younger than 60 years showed no correlation between resting heart rate and carotid plaque risk(all P>0.05).For different genders,the risk of carotid plaque increased significantly in male of Q5 group(OR= 1.58,95%CI:1.16-2.15),but there was no significant correlation between resting heart rate and carotid plaque risk in females(all P > 0.05).Conclusion The detection rate of carotid abnormality is relatively high in high-risk population of cardiovascular diseases in iangsu Province,and the risk of carotid plaque increases in high resting heart rate male and older age population.

关 键 词：静息心率 颈动脉斑块 心血管疾病 高危人群 

分 类 号：R543.4[医药卫生—心血管疾病]