纳米抗菌材料的研究进展  

Research progress of Nanometer Antibacterial Materials

作　　者：孔秋晨 佘慧明 杨粤军 KONG Qiuchen;SHE Huiming;YANG Yuejun(Department of Clinical Medicine,College of Medicine,Hunan Normal University,Changsha 410006,China)

机构地区：[1]湖南师范大学医学院临床医学系,湖南长沙410006

出　　处：《生物化工》2022年第1期158-163,共6页Biological Chemical Engineering

基　　金：湖南省自然科学基金(2021JJ3016);湖南省研究生科研创新项目(CX20200545);湖南省大学生创新训练计划项目(20211938);湖南师范大学大学生创新训练计划(2020136)。

摘　　要：随着抗生素的滥用以及超级细菌的出现,对新型抗菌药物的研发迫在眉睫。纳米抗菌材料以其独特的物理化学性质及优越的生物安全性在众多新兴抗菌药物中脱颖而出,纳米抗菌材料不仅可以直接杀伤细菌,同时也可以作为载体加强抗菌物质的抗菌作用,多项研究证明纳米抗菌材料在抗菌方面具有巨大发展潜力。本文对已报道的主要纳米抗菌材料(AMPs、金属基纳米材料、光介导的抗菌纳米材料、碳基纳米材料和2D NBG纳米材料)进行了回顾与总结,并简要阐述了各种材料的基本抗菌机制。Nowadays,with the abuse of antibiotics and the emergence of superbacteria,the research and development of new antibacterial drugs is extremely urgent.Nanometer antibacterial material with its unique physical and chemical properties and biological safety of superior in many emerging of antimicrobial agents,it can not only directly kill bacteria,but also can be used as a carrier to strengthen the antibacterial properties of antibacterial substances,a number of studies have confirmed that nanometer antibacterial materials in the field of antibacterial huge development potential.At this point,the current research of nanometer antibacterial material(AMPs,metal nanometer materials,light mediated antibacterial nano materials,carbon nanomaterials and 2D NBG nano material)has been reviewed and summarized,and briefly expounds the basic antimicrobial mechanism of various materials,including oxidative stress,mechanical damage,thermal/photocatalytic effect,etc.

关 键 词：纳米材料 耐药菌感染 抗菌 

分 类 号：R318.08[医药卫生—生物医学工程]