检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:Cyril Deroy Nicholas Stovall-Kurtz Federico Nebuloni Cristian Soitu Peter R.Cook Edmond J.Walsh
机构地区:[1]Department of Engineering Science,Osney Thermo-Fluids Laboratory,University of Oxford,Oxford OX20ES,UK [2]Sir William Dunn School of Pathology,University of Oxford,Oxford OX13RE,UK [3]Cold Spring Harbor Laboratory,Cold Spring Harbor,NY,USA
出 处:《Microsystems & Nanoengineering》2021年第6期119-127,共9页微系统与纳米工程(英文)
基 金:This work was supported by iotaSciences Ltd.(who provided financial support for C.D.,F.N.,and C.S.);the William H.G.FitzGerald Scholarship(N.S.‐K.);the Impact Acceleration Account of the Biotechnology and Biological Sciences Research Council(P.R.C.and E.J.W.);awards from the Medical Research Council under the Confidence in Concept scheme(MC_PC_15029 to P.R.C.and E.J.W).
摘 要:The aqueous phase in traditional microfluidics is usually confined by solid walls;flows through such systems are often predicted accurately.As solid walls limit access,open systems are being developed in which the aqueous phase is partly bounded by fluid walls(interfaces with air or immiscible liquids).Such fluid walls morph during flow due to pressure gradients,so predicting flow fields remains challenging.We recently developed a version of open microfluidics suitable for live-cell biology in which the aqueous phase is confined by an interface with an immiscible and bioinert fluorocarbon(FC40).Here,we find that common medium additives(fetal bovine serum,serum replacement)induce elastic no-slip boundaries at this interface and develop a semi-analytical model to predict flow fields.We experimentally validate the model’s accuracy for single conduits and fractal vascular trees and demonstrate how flow fields and shear stresses can be controlled to suit individual applications in cell biology.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.200