五味子降酶胶囊质量控制研究  

Study on quality control of Schisandra Transaminase reduction capsule

作　　者：任路路 姚大洋 任莹 李小伟[1] REN Lulu;YAO Dayang;REN Ying;LI Xiaowei(Preparation Room,The Traditional Chinese Medical Hospital of Taihe County,Fuyang,Anhui236600,China;Anhui Shouzheng Traditional Chinese Medicine Decoction Pieces Co.Ltd,Fuyang,Anhui 236600,China)

机构地区：[1]太和县中医院制剂室,安徽阜阳236600 [2]安徽守正中药饮片有限公司,安徽阜阳236600

出　　处：《安徽医药》2022年第4期676-679,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的 探讨五味子降酶胶囊的质量控制方法。方法 采用薄层色谱法(TLC)鉴别五味子降酶胶囊中的五味子、板蓝根;采用高效液相色谱法(HPLC)测定五味子中五味子醇甲的含量。结果 薄层鉴别斑点清晰,分离效果好,专属性强;含量测定中五味子醇甲在0.033 37~0.533 92μg范围内,与峰面积线性关系良好(r=0.999 5)。结论 方法操作简单,专属性和重现性良好,可作为五味子降酶胶囊的质量控制方法。Objective To explore the quality control method of Schisandra Transaminase reduction capsule.Methods The thin layer chromatography (TLC) method was used to identify qualitation for Schisandra chinensis and Radix isatidis in Schisandra Transaminase reduction capsule;high performance liquid chromatography (HPLC) method was used to determine the contents of Schisandrin A in Schisandra chinensis.Results The spot was clear in TLC identification with good separation effect and strong specificity.The content of Schisandrin A had a good linear relation with peak area (r=0.999 5),when ranged from 0.033 37 to 0.533 92μg.Conclusion The method is simple with good specificity and reproducibility,and can be used as the quality control for Schisandra Transaminase reduction capsule.

关 键 词：中草药 五味子属 色谱法 高效液相 色谱法 薄层 五味子降酶胶囊 板蓝根 五味子醇甲 

分 类 号：R286.0[医药卫生—中药学]