亚麻醉剂量丙泊酚对剖宫产术中内脏牵拉反射及新生儿窒息状况的影响  

Effect of anesthetic dose propofol on visceral traction response and neonatal asphyxia during cesarean section

作　　者：周结贤 梁俏丽 林爱娟 ZHOU Jie-xian;LIANG Qiao-li;LIN Ai-juan(Department of Anesthesiology,Zhuhai Maternal and Child Health Hospital,Zhuhai 519000,Guangdong,CHINA)

机构地区：[1]珠海市妇幼保健院麻醉科,广东珠海519000

出　　处：《海南医学》2022年第6期772-774,共3页Hainan Medical Journal

基　　金：广东省珠海市科技计划项目(编号:20181117E030072)。

摘　　要：目的 探讨亚麻醉剂量丙泊酚对剖宫产术中内脏牵拉反射及新生儿窒息状况的影响。方法 选择2020年3月至2021年3月珠海市妇幼保健院收治的150例拟行剖宫产手术的产妇为研究对象,根据随机数表法将产妇分为观察组和对照组各75例,观察组产妇在胎儿取出后给予5 mL丙泊酚静脉注射,对照组产妇给予0.1 mg/kg地佐辛静脉注射。比较术中两组产妇的内脏牵拉反射情况、新生儿窒息情况、新生儿1 min Apgar评分及产妇术后不良反应。结果 观察组产妇的内脏牵拉反射情况中1分与2分的总人数占比为96.00%,明显高于对照组的76.00%,差异有统计学意义(P<0.05);1 min Apgar评分为(8.34±1.03)分,明显高于对照组的(7.40±0.71)分,差异均有统计学意义(P<0.05);住院期间,观察组产妇出现恶心、呕吐、瘙痒、背痛等不良反应总发生率为6.67%,明显低于对照组的18.67%,差异有统计学意义(P<0.05)。结论 亚麻醉剂量的丙泊酚可有效降低剖宫产术中产妇的内脏牵拉反射,降低新生儿窒息的发生,值得在临床中推广。Objective To study the effect of anesthetic dose propofol on visceral traction response and neonatal asphyxia during cesarean section. Methods A total of 150 parturients undergoing cesarean section received in Zhuhai Maternal and Child Health Hospital from March 2020 to March 2021 were selected and divided into an observation group and a control group by random number table method, with 75 parturients in each group. Patients in the observation group were given 5 m L propofol intravenous injection after the fetus was taken out, and those in the control group were given 0.1 mg/kg dezocine intravenous injection. During the operation, the visceral traction response, neonatal asphyxia,neonatal 1 min Apgar score, and postoperative complications were compared between the two groups. Results In the observation group, the proportion of patients with visceral traction response score of 1 point and 2 points was 96.00% in the observation group, which was significantly higher than 76.00% in the control group(P<0.05). The 1 min Apgar score was(8.34±1.03) points, significantly higher than(7.40±0.71) points of the control group(P<0.05). During hospitalization, the total incidence of nausea, vomiting, itching, and back pain in the observation group was 6.67%, which was significantly lower than 18.67% in the control group(P<0.05). Conclusion The sub-anesthetic dose of propofol can effectively reduce the visceral traction response of the parturient during cesarean section and reduce the occurrence of neonatal asphyxia, which is worthy of clinical promotion.

关 键 词：剖宫产 亚麻醉剂量 丙泊酚 内脏牵拉反应 新生儿 窒息 

分 类 号：R719.8[医药卫生—妇产科学]