不同断脐机制对预防早产儿脑室内出血的网状meta分析  

Network meta-analysis of the effect of different umbilical cord severing mechanisms on the prevention of intraventricular hemorrhage in the preterm infants

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作  者:李苗苗 玄银河 钟清玲[3] 喻思思 LI Miaomiao;XUAN Yinhe;ZHONG Qingling;YU Sisi(School of Nursing,Catholic University of Pusan,Pusan 612-022,Korea;Yanbian No.2 People′s Hospital,Yanbian,Jilin 133000,China;School of Nursing,Nanchang University,Nanchang 330000,China;School of Nursing,Jiangxi University of Chinese Medicine,Nanchang,Jiangxi 330000,China)

机构地区:[1]韩国釜山加图立大学护理学院,韩国釜山612-022 [2]延边第二人民医院,吉林延边133000 [3]南昌大学护理学院,南昌330000 [4]江西中医药大学护理学院,南昌330000

出  处:《重庆医学》2022年第6期1035-1042,共8页Chongqing medicine

基  金:南昌大学教研课题(NCUJGLX-19-29)。

摘  要:目的采用网状meta分析不同断脐机制对降低早产儿脑室内出血及相关指标的效果。方法计算机检索PubMed、EMBASE、Cochrane图书馆、中国知网、万方、SinoMed数据库关于早产儿采用不同断脐的随机对照试验。使用STATA15.1和R软件对所得文献进行筛选、数据提取及质量评价,并进行网状meta分析。结果19项研究符合纳入标准,结果显示60 s断脐及脐带挤压对降低早产儿脑室内出血明显优于立即断脐(P<0.05);60~90 s断脐和脐带挤压组输血率明显低于立即断脐(P<0.05);不同断脐机制在降低早产儿死亡率方面无差异(P>0.05)。结论60~90 s断脐和脐带挤压是减少早产儿脑室内出血、改善缺血状态的理想干预措施。Objective To analyze the effects of different navel severing mechanisms on reducing intraventricular hemorrhage and related indexes in premature infants by the network meta-analysis.Methods PubMed,Embase,the Cochrane Library,China National Knowledge Infrastructure(CNKI),Wanfang Data and SinoMed,were searched to collect the randomized controlled trials of the premature infants with different navel amputations by computer.Stata15.1 and R software were used to screen the resulting literature,extract the data,evaluate the quality,and perform the network meta-analysis.Results A total of 19 studies met the inclusion criteria.The results showed that the delayed 60 s umbilical cord-cutting and umbilical cord squeezing were significantly better than immediate umbilical cord-cutting in reducing intraventricular hemorrhage in premature infants(P<0.05).The blood transfusion rate of 60-90 s umbilical cord-cutting and umbilical cord squeezing was significantly lower than that of immediate umbilical cord-cutting(P<0.05).There was no difference in reducing the mortality of premature infants with different umbilical severing mechanisms(P>0.05).Conclusion 60-90 s umbilical cord-cutting and umbilical cord squeezing are ideal interventions to reduce intraventricular hemorrhage and improve ischemic state in premature infants.

关 键 词:早产儿 胎盘输血 延迟断脐 脐带挤压 脑室内出血 网状meta分析 

分 类 号:R722.6[医药卫生—儿科]

 

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