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作 者:赵静 吴秀清[1] ZHAO Jing;WU Xiu-Qing(Children's Internal Medicine,Shenyang Children's Hospital,Shenyang 110032,China)
出 处:《中国药物经济学》2022年第2期88-90,94,共4页China Journal of Pharmaceutical Economics
摘 要:目的探讨小儿腹泻实施超短波联合药物灌肠治疗的临床效果。方法选取2019年2月至2021年1月沈阳市儿童医院收治的80例小儿腹泻患儿作为研究对象,按随机数字表法分为对照组和观察组,各40例。对照组实施药物灌肠治疗,观察组在对照组基础上加用超短波治疗,比较两组治疗有效率、炎症介质、免疫指标。结果观察组治疗有效率高于对照组,差异有统计学意义(P<0.05);两组治疗前白细胞介素-6(IL-6)、C反应蛋白(CRP)及肿瘤坏死因子-α(TNF-α)比较,差异无统计学意义(P>0.05);观察组患儿治疗后IL-6、TNF-α、CRP低于对照组,差异有统计学意义(P<0.05);两组治疗前免疫球蛋白M(IgM)、免疫球蛋白G(IgG)、免疫球蛋白A(IgA)比较,差异无统计学意义(P>0.05);观察组治疗后IgM、IgG、IgA低于对照组,差异有统计学意义(P<0.05)。结论小儿腹泻实施超短波联合药物灌肠治疗能够取得理想治疗效果,有助于改善患儿机体免疫功能,降低炎症介质水平,疗效显著。Objective To study the clinical effects of ultrashort wave combined with drug enema treatment for children with diarrhea.Methods Eighty children with diarrhea in children admitted to Shenyang Children’s Hospital between February 2019 and January 2021 were selected as observation objects,and were divided into a reference group and an analysis group by the computergenerated random number sampling method,with 40 cases each.Clinically carried out drug enema treatment and drug enema+ultrashort wave treatment respectively,and compared the total effective rate of treatment,inflammatory factor indicators,and immune indicators between groups.Results The total effective rate of the treatment of pediatric diarrhea in the analysis group was higher than that of the reference group,and the difference was statistically significant(P<0.05);the comparison of inflammatory factor indexes between the 2 groups before treatment was not statistically significant(P>0.05);The levels of IL-6,TNF-αand CRP in the observation group were lower than those in the control group after treatment,and the difference was statistically significant(P<0.05);the comparison of the immune indexes between the 2 groups before treatment,the difference was not statistically significant(P>0.05);IgM,IgG,and IgA in the observation group were lower than those in the control group after treatment,and the difference was statistically significant(P<0.05).Conclusion Ultrashort wave combined drug enema treatment for children with diarrhea can achieve the ideal therapeutic effect,which is helpful to improve the immune function of the children,reduce the level of inflammatory factors,and has a significant effect.
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