非危重型新型冠状病毒肺炎97例临床观察  

Clinical Observation on 97 Patients with Non-critical Type COVID-19

作　　者：时佳 叶晨[1] 杨宗国 陆云飞[1] 吕莹[1] 徐庆年[1] 汤伯宗[1] 殷科珊[1] 卢洪洲[1] 陈晓蓉[1] SHI Jia;YE Chen;YANG Zongguo;LU Yunfei;LYU Ying;XU Qingnian;TANG Bozong;YIN Keshan;LU Hongzhou;CHEN Xiaorong(Shanghai Public Health of Clinical Center,Shanghai 201508,China;Nanjing University of Chinese Medicine)

机构地区：[1]上海市公共卫生临床中心,上海201508 [2]南京中医药大学

出　　处：《西部中医药》2022年第3期5-8,共4页Western Journal of Traditional Chinese Medicine

基　　金：国家科技重大专项基金项目(2017ZX10305501);上海市卫计委“病毒性肺炎中医诊疗方案研究”项目(2018LQ014);上海市中医药管理局中医药防治新型冠状病毒肺炎应急专项(2020NCP001);中西医结合课题(ZHYY-ZXYJHZX-1-201703)。

摘　　要：目的:观察非危重型新型冠状病毒肺炎患者的临床特征,分析总结其发病规律及演变。方法:收集并分析97例上海市公共卫生临床中心收治住院的非危重型新型冠状病毒肺炎患者临床信息。结果:1)97例患者中男性占多数(54.64%),中位年龄为45岁,96.91%的患者有明确流行病学史。2)常见症状表现为发热(79.38%)、咳嗽/干咳(51.55%)、乏力(40.21%)、纳差(37.11%)、咽痛/痒(36.08%)、腹泻(24.74%)、出汗(22.68%)、鼻塞(17.53%)、头痛/晕(15.46%)、流涕(15.46%)。3)肺部CT以多肺叶病变为主,累及范围广;患者入院时白细胞、血小板、淋巴细胞计数、CD3、CD8、CD4、CD45淋巴细胞计数下降明显,与出院时比较,差异具有统计学意义(P<0.05);C反应蛋白、血沉、乳酸脱氢酶、肌红蛋白、触珠蛋白、酸性糖蛋白、纤维蛋白原、D-D二聚体明显升高,与出院时比较差异具有统计学意义(P<0.05)。4)所有患者均接受抗病毒治疗,94.85%的患者联合使用中药/中成药,35.05%的患者使用抗生素治疗。结论:97例非危重型新型冠状病毒肺炎患者呈病毒感染特征,预后大多良好。Objective:To analyze and sum up the pathogenesis and evolution of non-crtical type COVID-19 by observing clinical characteritistcs of the patients.Methods:Clinical information of 97 cases of non-critical type COVID-19,hospitalized in Shanghai public health of clinical center were collected.Results:1)Male are the most among 97 patients(54.64%),median age is 45 years old,96.91%of the patients have clear epidemiological histories.2)the common symptoms are fever(79.38%),cough/dry cough(51.55%),weakness(40.21%),poor appetite(37.11%),sore throat/pharyngeal itching(36.08%),diarrhea(24.74%),sweating(22.68%),nasal obstruction(17.53%),headache/vertigo(15.46%),runny nose(15.46%).3)pulmonary CT manifests multi lobe lesions mainly,involving a wide range.White blood cells(WBC),platelet and lymphocyte count,CD3,CD8,CD4,CD45 decreased notably when the patients were admitted,the difference had statistical meaning when compared with the discharge time(P<0.05);CRP,ESR,LDH,myoglobin,haptoglobin,acid glycoprotein,fibrinogen and D-D dimer increased significantly,and the difference showed statistical meaning(P<0.05).4)all the patients accepted antiviral therapy,94.85%of the patients were given with materia medica/Chinese patent medicine,and 35.05%were treated by antibiotics.Conclusion:All 97 patients with non-crtical type COVID-19 present the characteritics of viral infection,and most have a good prognosis.

关 键 词：新型冠状病毒 肺炎 临床特征 预后 

分 类 号：R254[医药卫生—中医内科学]