临床麻醉及术后镇痛应用右美托咪定和舒芬太尼的效果研究  

Effect of dexmedetomidine and sufentanil in clinical anesthesia and postoperative analgesia

作　　者：梁艳宁 周伟[1] LIANG Yan-ning;ZHOU Wei(Department of Surgical Anesthesia,Puyang Oilfield General Hospital,Puyang,Henan 457001,China)

机构地区：[1]濮阳市油田总医院手术麻醉科,河南濮阳457001

出　　处：《医药论坛杂志》2022年第1期48-51,共4页Journal of Medical Forum

基　　金：2019年河南省医学科技攻关计划省部共建项目(SB201904016)。

摘　　要：目的分析临床麻醉与术后镇痛中舒芬太尼与右美托咪定的应用效果。方法于濮阳市油田总医院2017年11月至2019年12月收治的手术患者中选取100例,按不同麻醉和镇痛方案将患者分为研究组和对照组各50例,给予芬太尼麻醉者为对照组,术后接受舒芬太尼镇痛,采用舒芬太尼进行手术麻醉者为研究组,术后镇痛联合应用舒芬太尼和右美托咪定,比较两组麻醉效果、术后疼痛程度以及麻醉后恢复情况。结果研究组麻醉优良率为96.0%,显著高于对照组的80.0%,组间差异有统计学意义(P<0.05)。研究组术后麻醉苏醒时间为(27.5±3.9)min,自主呼吸恢复时间为(9.2±1.8)min,气管拔除时间(8.1±2.3)min,均显著短于对照组(P<0.05)。研究组术后各时间点的VAS评分与对照组比较,差异有统计学意义(P<0.05)。研究组与对照组并发症发生率分别为4.0%和18.0%,差异具有统计学意义(P<0.05)。结论舒芬太尼应用于手术麻醉,术后镇痛联合应用右美托咪定,可改善患者预后,使患者并发症的发生显著减少,同时使患者术后疼痛得到有效减轻。Objective To analyze the efficacy of sufentanil and dexmedetomidine in clinical anesthesia and postoperative analgesia.Methods A total of 100 surgical patients admitted to our hospital from November 2017 to December 2019 were selected and randomly divided into two groups. The control group received fentanyl anesthesia and postoperative sufentanil analgesia;the study group received sufentanil for surgical anesthesia and combined sufentanil and dexmedetomidine for postoperative analgesia. The anesthesia effect, postoperative pain and postoperative recovery were compared between the two groups.Results The rate of excellent and good anesthesia in the study group was 96.0%, which was significantly higher than that in the control group(80.0%), and the difference was significant(P<0.05). The recovery time after anesthesia in the study group was(27.5±3.9) min, the recovery time of spontaneous breathing was(9.2±1.8) min, trachea extraction time was(8.1±2.3) min, were significantly shorter than those of the control group(P<0.05). The VAS score of the study group at each time point after operation was significantly different from that of the control group(P<0.05). The incidence of complications in study group and control group was 4.0% and 18.0%, respectively, with significant difference(P<0.05).Conclusion Sufentanil applied in surgical anesthesia and combined with dexmedetomidine in postoperative analgesia can effectively relieve postoperative pain, reduce complications and improve the prognosis of patients.

关 键 词：右美托咪定 临床麻醉 舒芬太尼 术后镇痛 应用效果 

分 类 号：R614[医药卫生—麻醉学]