超声辅助提取水飞蓟素的工艺优化  

Process Optimization of Ultrasonic-assisted Extraction of Silymarin

作　　者：李国源 王琳丽 陈海蛟[1] Li Guoyuan;Wang Linli;Chen Haijiao(Jilin Agricultural Science and Technology University, Jilin 132101, China)

机构地区：[1]吉林农业科技学院,吉林吉林132101

出　　处：《黑龙江科学》2022年第6期17-19,共3页Heilongjiang Science

基　　金：省级大学生科技创新创业训练计划项目(吉农院合字[2020]第045号)。

摘　　要：为探寻超声辅助提取水飞蓟素的最佳工艺条件,分别考察了提取溶剂、提取时间、提取温度、料液比对水飞蓟素提取率的影响,确定了最佳提取条件为:以无水乙醇为溶剂,时间1.5 h,温度65℃,药材和有机溶剂比为1∶14 g/mL,得到的水飞蓟素含量为35.11 mg/g。研究表明,该制备工艺合理,稳定可行,可用于水飞蓟素的提取。In order to explore the optimal technological condition of ultrasonic-assisted extraction of silymarin,the study analyzes the influencing of extraction solvent,extraction time,extraction temperature,feed liquid on the extraction efficiency of silymarin;and determines the optimal extraction condition is as follows,i.e.absolute ethyl alcohol is as solvent in 1.5 h and under 65℃,the ratio of medicinal materials on organic solvent is 1∶14 g/mL,and silymarin is 35.11 mg/g.The study shows that the preparation technology is rational and stable,so it can be used to extract silymarin.

关 键 词：水飞蓟素 超声提取 正交试验 

分 类 号：R284.2[医药卫生—中药学]