超重与高动脉僵硬度的相关性研究  

Association between overweight and high arterial stiffness

作　　者：许文哲 谢予晨 陈晴晴 沙蕾 杜联芳[3] 李朝军[3] Xu Wenzhe;Xie Yuchen;Chen Qingqing;Sha Lei;Du Lianfang;Li Zhaojun(Department of Ultrasonography,Zibo Central Hospital,Zibo 255036,Shandong Province,China)

机构地区：[1]淄博市中心医院超声科,255036 [2]上海交通大学附属第一人民医院嘉定分院超声科 [3]上海交通大学附属第一人民医院超声科

出　　处：《中华老年心脑血管病杂志》2022年第3期269-272,共4页Chinese Journal of Geriatric Heart,Brain and Vessel Diseases

基　　金：上海市自然科学基金(21ZR1451400);上海市松江区科技攻关项目(18SJKJGG53)。

摘　　要：目的探讨超重与高动脉僵硬度发生率的关系。方法选取2020年8月~2020年12月于上海交通大学附属第一人民医院嘉定分院健康体检的自然人群中无心脑血管事件者2418例,根据入选者体质量指数(BMI)分为肥胖组258例,超重组792例和对照组1368例。收集入选者一般临床资料及动脉波速指数(AVI)等。结果肥胖组和超重组女性AVI及高动脉僵硬度发生率明显高于男性(20.5±8.0 vs 17.0±5.2,19.6±6.8 vs 18.6±6.1;5.4%vs 0.8%,2.9%vs 1.6%,P<0.05)。肥胖组和超重组女性AVI及高动脉僵硬度发生率明显高于对照组女性(P<0.05)。肥胖组男性AVI和高动脉僵硬度发生率明显低于超重组和对照组男性(P<0.05)。超重组65~79岁人群高动脉僵硬度发生率低于肥胖组和对照组(1.3%vs 3.9%、2.8%,P<0.05)。在整体受试者中,超重是高动脉僵硬度的独立保护因素(P=0.001)。分别在肥胖组、超重组和对照组中,年龄、收缩压是高动脉僵硬度的独立危险因素,身高和脉搏是高动脉僵硬度的独立保护因素(P<0.05,P<0.01)。结论女性超重和肥胖者的AVI和高动脉僵硬度发生率均增高,男性超重和肥胖者高动脉僵硬度发生率减低。Objective To study the association between overweight and incidence of high arterial stiffness.Methods A total of 2418 people without cardiovascular and cerebrovascular events who underwent physical examination in Affiliated No.1 People’s Hospital Jiading Branch of Shanghai Jiaotong University from August 2020 to December 2020 were divided into obesity group(n=258),overweight group(n=792) and control group(n=1368) according to their BMI.Their general clinical data and AVI were recorded.Results The AVI and incidence of high arterial stiffness were significantly higher in females than in males of obesity and overweight groups(20.5±8.0 vs 17.0±5.2,19.6±6.8 vs 18.6±6.12,5.4% vs 0.8%,2.9% vs 1.6%,P<0.05) and in females of obesity and overweight groups than in those of control group(P<0.05).The AVI and incidence of high arterial stiffness were significantly lower in males of obesity group than in males of overweight and control group(P<0.05).The incidence of high arterial stiffness was significantly lower in 65-79 years old people of overweight group than in those of obesity group and control group(1.3% vs 3.9%,2.8%,P<0.05).Overweight was an independent protective factor for high arterial stiffness in the 2418 people included in this study(P=0.001).Age and SBP were independent risk factors for high arterial stiffness while body height and pulse were independent protective factors for high arterial stiffness in three groups(P<0.05,P<0.01).Conclusion The AVI and incidence of high arterial stiffness are high in overweight and obesity females while the incidence of high arterial stiffness is low in overweight and obesity males.

关 键 词：人体质量指数 肥胖症 高血压 动脉粥样硬化 

分 类 号：R543.5[医药卫生—心血管疾病] R589.2[医药卫生—内科学]