Computationally predicted pathogenic USP9X mutation identified in infertile men does not affect spermatogenesis in mice  

作　　者：Wei Liu Yue-Wen Wang Huan Zhang Xue-Feng Xie Ao Ma Qumar Zaman Abdul Rafay Javed Tanveer Abbas Wasim Shah Riaz Ahmad Da-Ren Zhao Hui Ma Muhammad Zubair Ranjha Khan Qing-Hua Shi 

机构地区：[1]Division of Reproduction and Genetics,First Affiliated Hospital of USTC,Hefei National Laboratory for Physical Sciences at Microscale,CAS Key Laboratory of Innate Immunity and Chronic Disease,School of Basic Medical Sciences,Division of Life Sciences and Medicine,Biomedical Sciences and Health Laboratory of Anhui Province,CAS Center for Excellence in Molecular Cell Science,Collaborative Innovation Center of Genetics and Development,University of Science and Technology of China,Hefei,Anhui 230027,China [2]Medical Genetics Research Laboratory,Department of Biotechnology,Quaid-i-Azam University,Islamabad 45320,Pakistan

出　　处：《Zoological Research》2022年第2期225-228,共4页动物学研究(英文)

基　　金：supported by the Fundamental Research Funds for the Central Universities(WK2070080005)。

摘　　要：Infertility is a major health issue,affecting approximately 15%of couples of child-bearing age.Although nearly half of idiopathic infertility cases are assumed to have a genetic basis,the underlying causes remain largely unknown in most infertile men.

关 键 词：TILE assumed USP9X 

分 类 号：R698.2[医药卫生—泌尿科学]