双波长脉冲染料激光联合30%超分子水杨酸治疗中重度痤疮的效果  

Clinical efficacy of 30% supramolecular salicylic acid combined with dual-wavelength pulsed dye laser in treatment of moderate to severe acne

作　　者：黄晴 胡丽[1] 刘林[1] 蒲以欢 张玉洁 李倩[1] 邵馨怡 张灵曌 陈瑾[1] 陈阳美[1] Huang Qing;Hu Li;Liu Lin;Pu Yihuan;Zhang Yujie;Li Qian;Shao Xinyi;Zhang Lingzhao;Chen Jin;Chen Yangmei(Department of Dermatology,the First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)

机构地区：[1]重庆医科大学附属第一医院皮肤科,重庆400016

出　　处：《中华医学美学美容杂志》2022年第1期5-8,共4页Chinese Journal of Medical Aesthetics and Cosmetology

基　　金：国家自然科学基金(82073462)。

摘　　要：目的:探讨双波长脉冲染料激光联合30%超分子水杨酸治疗面部中重度痤疮的疗效及安全性。方法:2020年5月至2021年1月,重庆医科大学附属第一医院皮肤科就诊的中重度痤疮患者60例,男24例、女36例;年龄18~40(26±4)岁,分为观察组和对照组,每组30例。观察组予以水杨酸两周治疗1次共6次;另外加双波长脉冲染料激光每月治疗1次共3次。对照组仅予以双波长脉冲染料激光治疗,每月治疗1次共3次。结果:观察组有效22例,占73.3%,对照组有效14例,占46.7%,观察组疗效优于对照组,差异有统计学意义(χ2=4.44,P<0.05)。两组患者均未出现明显不良反应。结论:双波长脉冲染料激光联合30%超分子水杨酸治疗面部中重度痤疮疗效较好、安全性高,值得临床应用。Objective To investigate the efficacy and safety of dual wavelength pulsed dye laser combined with 30%supramolecular salicylic acid in the treatment of moderate and severe facial acne.Methods Sixty patients with moderate and severe acne that visited the Dermatology Department of the First Affiliated Hospital of Chongqing Medical University from May 2020 to January 2021,were selected and randomly divided into observation group and control group,with 30 patients in each group.The observation group was given dual-wavelength pulsed dye laser combined with 30%supramolecular salicylic acid.30%supramolecular salicylic acid was used once every two weeks,for a total of six times.Dual-wavelength pulsed dye laser was given once a month,for a total of three times.The control group was only given dual-wavelength pulsed dye laser,once a month,a total of three times.Results Twenty-two cases(73.33%)in the observation group were effective,while 14 cases(46.67%)in the control group were effective.The efficacy of the observation group was better than that of the control group,and the difference was statistically significant(χ2=4.44,P<0.05).There were no obvious adverse reactions in both groups.Conclusions Dual-wavelength pulsed dye laser combined with 30%supramolecular salicylic acid is effective and safe in the treatment of moderate and severe facial acne,which is worth popularizing.

关 键 词：寻常痤疮 治疗结果 超分子水杨酸 脉冲染料激光 疗效 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]