S-100吸收性止血绫在神经外科开颅手术中的临床应用  

Clinical Application of S-100 Absorptive Hemostatic Damask in Neurosurgery Craniotomy

作　　者：赵胜 ZHAO Sheng(The Second People’s Hospital of Guiyang,Guiyang 550002,China)

机构地区：[1]贵阳市第二人民医院,贵州贵阳550002

出　　处：《中外医学研究》2022年第7期153-156,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:评价S-100可吸收止血材料在神经外科开颅手术止血中的应用价值。方法:选取贵阳市第二人民医院神经外科在2018年1月-2021年8月需行开颅手术患者764例,根据止血方式的不同分为对照组(n=382)和研究组(n=382)。研究组使用S-100可吸收止血材料进行止血,对照组止血材料为明胶海绵。对比两组粘连情况、术中出血量、止血有效率和手术时间,以及术后不良反应和认知功能(MMSE)评分。结果:研究组粘连9例(2.36%)、手术时间(1.60±0.50)h、术中总出血量(166.20±17.85)ml、止血有效375例(98.17%),对照组分别为24例(6.28%)、(2.05±0.65)h、(210.30±20.68)ml、337例(88.22%),研究组均优于对照组,差异均有统计学意义(P<0.05);研究组术后不良反应发生5例(1.31%),对照组发生47例(12.30%),研究组术后不良反应发生率较低,差异有统计学意义(P<0.05);研究组MMSE评分(24.08±2.91)分,明显高于对照组的(20.19±2.05)分,差异均有统计学意义(P<0.05)。结论:S-100止血绫止血迅速,明显减少术中出血量,并降低术后不良反应发生率,改善患者认知功能,值得大力推广。Objective:To evaluate the application value of S-100 absorbable material in neurosurgery craniotomy for hemostasis.Method:A total of 764 neurosurgical patients who needed craniotomy from January 2018 to August 2021 in the Second People’s Hospital of Guiyang were selected and divided into the control group(n=382)and the study group(n=382)according to different hemostatic methods.The study group used S-100 absorptive hemostatic damask for hemostasis,and the control group used gelatin sponge for hemostasis.The differences in adhesion during the operation,intraoperative blood loss,bleeding effective rate and operation time between the two groups,as well as the differences in postoperative adverse reactions and cognitive function(mini-mental state examination,MMSE)score were compared between the two groups.Result:In the study group,there were 9 cases(2.36%)of adhesions,operation time(1.60±0.50)h,intraoperative blood loss(166.20±17.85)ml,effective rate of hemostasis in 375 cases(98.17%),and 24 cases(6.28%),(2.05±0.65)h,(210.30±20.68)ml,337 cases(88.22%)in the control group,the indexes in the study group were better than those in the control group,the differences were statistically significant difference(P<0.05).The postoperative adverse reactions in the study group was 5 cases(1.31%),while there were 47 cases(12.30%)in the control group,the rate of postoperative adverse reactions in the study group was lower than that in the control group,the difference was statistically significant difference(P<0.05).The MMSE score of the study group was(24.08±2.91)points,which was significantly higher than(20.19±2.05)points of the control group,the difference was statistically significant difference(P<0.05).Conclusion:S-100 hemostasis can stop bleeding quickly,greatly less the amount of intraoperative blood loss,and at the same time reduce the postoperative adverse reactions rate,and improve patients’cognitive function.It is worthy of vigorous promotion.

关 键 词：S-100止血材料 电凝止血 神经外科 止血效果 

分 类 号：R651.1[医药卫生—外科学]