成分输血对产科DIC患者临床效果及凝血功能的影响  

Influence of Component Blood Transfusion on Clinical Effect and Coagulation Function in Obstetric DIC Patients

作　　者：张筠 林小兰 李丽红 ZHANG Yun;LIN Xiaolan;LI Lihong(不详;The Second Hospital of Longyan,Longyan 364000,China)

机构地区：[1]龙岩市第二医院,福建龙岩364000

出　　处：《中外医学研究》2022年第8期120-123,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:对产科弥散性血管内凝血(DIC)患者应用成分输血所得效果及该输血方式对患者凝血功能的影响进行研究。方法:对2019年1月-2021年8月龙岩市第二医院接收的84例DIC患者临床诊疗资料进行回顾性分析,依据其采用的输血方式作为分组标准,将采取全血输血的42例患者纳入对照组,将采用成分输血的42例患者纳入观察组。比较两组DIC患者治疗效果、治疗前后凝血功能相关指标[血浆组织因子(TF)、凝血酶-抗凝血酶复合物(TAT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)]水平及治疗期间不良反应(休克、皮疹、非溶血性发热或寒战)发生率。结果:观察组抢救成功率高于对照组,子宫切除率低于对照组(P<0.05),两组新生儿死亡率差异无统计学意义(P>0.05);输血前,两组TF、TAT、PT、APTT水平差异均无统计学意义(P>0.05),输血后3 h,观察组TF、TAT、PT、APTT水平均低于对照组(P<0.05);观察组不良反应总发生率为4.76%,低于对照组的23.81%(P<0.05)。结论:成分输血可有效改善产科DIC患者凝血功能,有效遏制DIC病情发展,抢救成功率较高,可有效改善患者凝血功能,与常规全血输血相比,该输血方式在输血安全性上也具有较显著的优势。Objective:To study the effect of component blood transfusion in obstetric patients with diffuse intravascular coagulation(DIC)and the effect of this blood transfusion on the coagulation function of patients.Method:The clinical diagnosis and treatment data of 84 patients with DIC received in the Second Hospital of Longyan from January 2019 to August 2021 were retrospectively analyzed.According to the blood transfusion method as the grouping standard,42 patients who received whole blood transfusion were included in the control group,42 patients who received component blood transfusion were included in the observation group.The treatment effect of the two groups of DIC patients,blood coagulation related indicators before and after treatment[plasma tissue factor(TF),thrombin-antithrombin complex(TAT),prothrombin time(PT),activated partial thromboplastin time(APTT)]and the incidence of adverse reactions(shock,rash,non-hemolytic fever or chills)during treatment in two groups were compared.Result:The rescue success rate of the observation group was higher than that of the control group,and the rate of hysterectomy were lower than those of the control group(P<0.05).There was no significant difference in neonatal mortality between the two groups(P>0.05).Before blood transfusion,there were no significant differences in the levels of TF,TAT,PT,and APTT between the two groups(P>0.05).3 h after blood transfusion,the levels of TF,TAT,PT,and APTT in the observation group were lower than those in the control group(P<0.05).The total incidence of adverse reactions in the observation group was 4.76%,which was lower than 23.81%in the control group(P<0.05).Conclusion:Component blood transfusion can effectively improve the blood coagulation function of obstetric DIC patients,effectively curb the development of DIC,and has a higher rescue success rate.It can effectively improve the blood coagulation function of patients.Compared with conventional whole blood transfusion,this blood transfusion method also has the safety of blood transfu

关 键 词：产科 弥散性血管内凝血 全血输血 成分输血 凝血功能 

分 类 号：R714.254[医药卫生—妇产科学]