Direct C(sp^(3))-H Sulfonylation of Xanthene Derivatives with Sodium Sulfinates by Oxidative Copper Catalysis  

作　　者：Qinghao Song He Zhao Yanping Sun Huanfeng Jiang Min Zhang 

机构地区：[1]Key Lab of Functional Molecular Engineering of Guangdong Province,School of Chemistry and Chemical Engineering,South China University of Technology,Guangzhou,Guangdong 510640,China

出　　处：《Chinese Journal of Chemistry》2022年第3期371-377,共7页中国化学（英文版）

基　　金：the National Natural Science Foundation of China(No.21971071);the Natural Science Foundation of Guangdong Province(No.2021A1515010155);the Fundamental Research Funds for the Central Universities(No.2020ZYGXZR075).

摘　　要：By employing a readily available CuCI/DDQ catalyst system,we herein report a direct C(sp^(3))-H sulfonylation of xanthene derivates with odorless sodium sulfinates.Various 9H-xanthenes,thioxanthenes,and 9,10-dihydroacridines are efficiently transformed into the desired benzylic sulfonyl products via a radical/radical cross-coupling process,proceeding with the merits of broad substrate scope,operational simplicity,good functional group compatibility,and mild reaction conditions.

关 键 词：Oxidation C(sp^(3))-H sulfonylation HETEROCYCLES Radical reactions Sodium sulfinates 

分 类 号：O62[理学—有机化学]