Strategies for Inhibition and Disaggregation of Amyloid-β Fibrillation  

作　　者：Hao Geng Dong Gao Zijuan Wang Xiaoning Liu Zhanshuo Cao Chengfen Xing 

机构地区：[1]School of Materials Science and Engineering,Hebei University of Technology,Tianjin 300130,China [2]Key Laboratory of Hebei Province for Molecular,Biophysics Institute of Biophysics,School of Science,Hebei University of Technology,Tianjin 300130,China [3]College of Chemical Engineering,Hebei University of Technology,Tianjin 300130,China

出　　处：《Chinese Journal of Chemistry》2022年第4期524-538,共15页中国化学（英文版）

基　　金：the financial support from the National Natural Science Foundation of China(Nos.21773054,21905072 and 22077025);the Natural Science Foundation of Hebei Province(Nos.B2020202062 and B2020202086).

摘　　要：Comprehensive Summary Amyloid-β protein(Aβ)is a fatal cause of Alzheimer's disease,which can trigger a series of cytotoxicity by the abnormal aggregation of Aβ in human brain.The strategies for inhibition and disaggregation of Aβ fibrillation are mostly based on the interaction between monomers,oligomers,fibrils,and materials.

关 键 词：Amyloid beta-peptides Inhibition and disaggregation Materials science PHOTOOXIDATION Photothermal effect 

分 类 号：TB3[一般工业技术—材料科学与工程]