Zfp281 is essential for epiblast maturation through a cell autonomous effect  

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作  者:Ruge Zang Xin Huang Dan Li Hongwei Zhou Shaorong Gao Jianlong Wang 

机构地区:[1]Clinical and Translational Research Center of Shanghai First Maternity and Infant Hospital,School of Life Sciences and Technology,Tongji University,Shanghai 200092,China [2]Department of Medicine,Columbia Center for Human Development,Columbia Stem Cell Initiative,Herbert Irving Comprehensive Cancer Center,Columbia University Irving Medical Center,New York,NY 10032,USA

出  处:《Journal of Genetics and Genomics》2022年第1期85-88,共4页遗传学报(英文版)

基  金:funded by grants from the National Institutes of Health (R01GM129157, R01HD095938, R01HD097268, and R01HL146664);by contracts from New York State Stem Cell Science (NYSTEM#C35583GG and C35584GG)。

摘  要:Pluripotency is recognized as a spectrum of cellular states spanning the na?ve pluripotency established in the preimplantation blastocyst and its transition into primed pluripotency in the postimplantation epiblast cells. The exit from pluripotency is followed by the initiation of gastrulation(Brennan et al., 2001;Nichols and Smith, 2009).

关 键 词:IMPLANTATION AUTONOMOUS EFFECT 

分 类 号:Q25[生物学—细胞生物学]

 

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