正电子类药物全自动核素分装仪的研究进展  

Research progress of positron radiopharmaceutical automatic nuclide packing instrument

作　　者：蒋皆恢 代双杰 左传涛 Jiang Jiehui;Dai Shuangjie;Zuo Chuantao(Key Laboratory of Specialty Fiber Optics and Optical Access Networks,Joint International Research Laboratory of Specialty Fiber Optics and Advanced Communication,School of Information and Communication Engineering,Shanghai University,Shanghai 200444,China;PET Center,Huashan Hospital,Fudan University,Shanghai 200235,China)

机构地区：[1]上海大学通信与信息工程学院特种光纤与光接入网重点实验室,特种光纤与先进通信国际合作联合实验室,200444 [2]复旦大学附属华山医院PET中心,上海200235

出　　处：《国际放射医学核医学杂志》2021年第10期648-653,共6页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：上海市科委生物医药领域重点支撑计划(19441903500)。

摘　　要：近年来, 我国核医学事业飞速发展, 放射性核素被广泛地应用于肿瘤、心脏疾病和神经疾病的诊疗中。正电子类药物分装是核医学诊疗前的必要步骤。由于手工分装会对核医学工作者造成一定的核辐射以及产生抽取剂量准确性等问题, 因此研制全自动核素分装仪具有重要的临床价值。笔者系统回顾了全自动核素分装仪的发展历程, 重点阐述现有产品在核素分装、原液稀释、气泡检测方面的功能, 并提出现有产品存在的维护困难、价格昂贵、功能不完善等不足, 最后对正电子类药物全自动核素分装仪在核素注射、核素剂量计算、功能模块化等未来发展方向上的应用进行了展望。In recent years,with the rapid development of nuclear medicine in China,radionuclides have been widely used in the diagnosis and treatment of tumors,heart diseases,and neurodegenerative diseases.Positron radiopharmaceutical nuclide packing is a necessary step before diagnosis and treatment can be performed in nuclear medicine clinics.Given that the process of manual packing would expose nuclear medicine workers to nuclear radiation,the development of an automatic nuclide packing instrument is of great clinical value.The development process of the automatic nuclide packaging instruments was reviewed;the functions of existing products,including nuclide packing,stock solution dilution,and bubble detection,were demonstrated;and problems in existing products,including maintaining difficulties,expensive costs,and insufficient functions,were identified.Finally,this paper discussed the prospects for the future development directions of nuclide packing,such as combining nuclide injection,nuclide quantity calculation,functional modularization,and others.

关 键 词：核医学 放射性药物 辐射防护 效率 自动分装仪 

分 类 号：R817[医药卫生—影像医学与核医学]