放射性骨损伤的研究进展  

Research progress on radiation-induced bone injury

作　　者：徐非 程蕊棠 缪孙涵 邱丽颖 Xu Fei;Cheng Ruitang;Miao Sunhan;Qiu Liying(Department of Basic Medicine,Wuxi Medical School,Jiangnan University,Wuxi 214122,China)

机构地区：[1]江南大学无锡医学院基础医学系,214122

出　　处：《国际放射医学核医学杂志》2021年第9期591-596,共6页International Journal of Radiation Medicine and Nuclear Medicine

基　　金：江苏省自然科学基金(BK20190597);中国博士后科学基金面上资助(2019M661729)。

摘　　要：射线照射是现代医疗中常用的方法之一,尤其在恶性肿瘤的治疗中应用广泛。但在放疗过程中,射线可对骨相关细胞、骨微观结构产生直接影响,或对骨髓、脉管系统等产生间接影响,从而造成骨损伤。尽管目前的研究成果对放射性骨损伤的认识并不透彻,但因其具有普遍性,故近年来逐渐受到医疗工作者的重视。笔者对射线引起的骨骼系统损伤及其预防和治疗进行综述。Radiation is one of the commonly used methods in modern medical treatment,especially in the treatment of malignant tumors.However,in the process of radiotherapy,radiation directly affect bone-related cells and bone microstructure,or indirectly affect bone marrow and vascular system,resulting in bone injury.Although the current research results do not have a thorough understanding of radiation-induced bone injury,it has gradually recevied attention from medical workers in recent years because of its universality.The bone system injury caused by radiation and its prevention and treatment are reviewed in this paper.

关 键 词：放射疗法 辐射损伤 放射性骨坏死 骨折 骨损伤 骨质流失 骨生物力学 

分 类 号：R818[医药卫生—放射医学]