Construction of anion-functionalized hypercrosslinked ionic porous polymers for efficient separation of bioactive molecules  

阴离子功能化超交联离子多孔聚合物的构建及生物活性物质高效分离

作　　者：Xian Suo Yuqi Huang Zhenkang Li Hanqian Pan Xili Cui Huabin Xing 锁显;黄玉琦;李侦糠;潘罕骞;崔希利;邢华斌(Key Laboratory of Biomass Chemical Engineering of Ministry of Education,College of Chemical and Biological Engineering,Zhejiang University,Hangzhou,310027,China)

机构地区：[1]Key Laboratory of Biomass Chemical Engineering of Ministry of Education,College of Chemical and Biological Engineering,Zhejiang University,Hangzhou,310027,China

出　　处：《Science China Materials》2022年第4期1068-1075,共8页中国科学（材料科学（英文版）

基　　金：financially supported by the National Natural Science Foundation of China(21908191,21938011,21890764);Zhejiang Provincial Natural Science Foundation of China(LR20B060001);the Entrepreneur Team Introduction Program of Zhejiang(2019R01006)。

摘　　要：Porous ionic polymers have demonstrated great potential for high-performance separation by the merits of their unique molecular recognition,but the preparation of anion-functionalized ionic polymers for the separation of bioactive molecules with highly similar structures remains a challenge.Here,through the facile Friedel-Crafts alkylation between benzylimidazole ionic liquids(ILs)and crosslinkers,several anion-functionalized hypercrosslinked ionic porous polymers(HIPs)are reported,which are well decorated with strongly basic carboxylate anions as well as feature tubular morphology and excellent thermal stability.High adsorption capacity(103.6 mg g^(−1) for tocopherol homologues)and selectivity(S_(βγ/α),4.26;S_(δ/α),3.19)for bioactive compounds with high structural similarity have been realized,superior to those of commercial adsorbents,hypercrosslinked polymer without ILs,and HIPs with common ILs.This study manifests a new synthetic strategy and rational molecular design for functionalized adsorbents,as well as offers new opportunities to enable high-performance separation.多孔离子聚合物由于其独特的分子识别能力在高效分离中表现出巨大的潜力,但制备阴离子功能化离子聚合物用于结构高度相似生物活性物质分离仍然具有挑战.本文通过苄基咪唑离子液体与交联剂发生简易的Friedel-Crafts烷基化反应,报道了一类具有强碱羧酸阴离子功能化、管状形貌和高热稳定性的超交联离子多孔聚合物(HIPs).实现了对结构高度相似的生物活性化合物的高容量(生育酚同系物:103.6 mg g^(−1))和高选择性(S_(βγ/α),4.26;S_(δ/α),3.19)吸附分离,其性能优于商业吸附剂、不含离子液体的超交联聚合物和含常规离子液体的HIPs.本研究展示了功能化吸附剂新的合成策略和合理的分子设计,为实现高效分离提供了新的机会.

关 键 词：anion-functionalization hypercrosslink porous ionic polymers adsorption tocopherol homologues phenolic compounds 

分 类 号：O631.5[理学—高分子化学] O647.33[理学—化学]