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作 者:孙娜 陶翠云 SUN Na;TAO Cui-yun(Department of No.1 Pediatrics,Gaotang County People's Hospital,Liaocheng Shandong Province 252800,China)
机构地区:[1]高唐县人民医院小儿一科,山东聊城252800
出 处:《中国城乡企业卫生》2021年第12期1-3,共3页Chinese Journal of Urban and Rural Enterprise Hygiene
摘 要:目的分析急性肠胃炎患儿应用头孢克肟联合肠炎宁糖浆的治疗效果。方法选取高唐县人民医院2019年7月—2020年7月诊治的90例急性肠胃炎患儿临床资料,按随机数字表法分为研究组和对照组各45例,对照组给予头孢克肟治疗,研究组给予头孢克肟联合肠炎宁糖浆治疗,分析两组疗效、症状持续时间及降钙素原(PCT)水平。结果治疗后,研究组总有效率为97.78%,高于对照组的82.22%,差异有统计学意义(χ^(2)=4.444 4,P<0.05);研究组腹痛、呕吐、发热和腹泻持续时间分别为(3.54±1.08)、(1.79±0.87)、(1.75±0.63)和(2.52±0.68)d,均低于对照组的(5.16±1.13)、(2.73±0.91)、(2.92±0.95)和(3.86±0.93)d,差异均有统计学意义(t=6.952 4、5.008 6、6.885 3、7.802 4,P<0.05);研究组PCT水平为(2.16±0.68)ng/ml,低于对照组的(4.23±1.36)ng/ml,差异有统计学意义(t=9.132 4,P<0.05)。结论急性肠胃炎患儿应用头孢克肟与肠炎宁糖浆联合治疗,可缩短症状的持续时间,提升临床疗效,降低PCT水平,值得临床推广应用。Objective To analyze the therapeutic effect of cefixime combined with Changyanning syrup in children with acute gastroenteritis. Methods The clinical data of 90 children with acute gastroenteritis diagnosed and treated in Gaotang County People’s Hospital from July 2019 to July 2020 were selected and divided into study group and control group with 45 cases in each group according to random number table method. The control group was treated with cefixime and the study group was treated with cefixime combined with Changyanning syrup. The curative effect,symptom duration and procalcitonin(PCT)level of the two groups were analyzed. Results After treatment,the total effective rate of the study group was 97.78%,higher than 82.22% of the control group,and the difference was statistically significant (χ^(2)=4.444 4,P<0.05);the duration of abdominal pain,vomiting,fever and diarrhea in the study group were(3.54±1.08),(1.79±0.87),(1.75±0.63)and(2.52±0.68)days,respectively,which were lower than those in the control group with(5.16±1.13),(2.73±0.91),(2.92±0.95),(3.86±0.93)days,and the differences were statistically significant(t=6.952 4,5.008 6,6.885 3,7.802 4,P<0.05);the PCT level in the study group was(2.16±0.68)ng/ml,which was lower than that in the control group with(4.23±1.36)ng/ml,and the difference was statistically significant(t=9.132 4,P<0.05). Conclusion The combined treatment of cefixime and Changyanning syrup in children with acute gastroenteritis could reduce the duration of symptoms,improve the clinical efficacy,and reduce the level of PCT,which was worthy of clinical promotion and application.
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