甲状腺毒性周期性麻痹患者反跳性高钾血症三例报道并文献复习  

Rebound Hyperkalemia in Patients with Thyrotoxic Periodic Paralysis:Three Cases Reports and Literature Review

作　　者：袁海霞 贺春燕 张晶[2] 周锋[2] YUAN Haixia;HE Chunyan;ZHANG Jing;ZHOU Feng(School of Medicine,Wuhan University of Science and Technology,Wuhan 430081,China;Department of Endocrinology,Puren Hospital of Wuhan University of Science and Technology,Wuhan 430081,China)

机构地区：[1]武汉科技大学医学院,湖北省武汉市430081 [2]武汉科技大学附属普仁医院内分泌科,湖北省武汉市430081

出　　处：《中国全科医学》2022年第15期1910-1913,共4页Chinese General Practice

基　　金：湖北省卫生健康科研基金资助项目(WJ2019H222)。

摘　　要：甲状腺毒性周期性麻痹(TPP)是由甲状腺毒症引起的一种内分泌急症,主要表现为周期性肌无力和低钾血症,严重威胁患者健康。血钾降低的水平与TPP患者肌无力的严重程度密切相关,补钾治疗能快速缓解患者的肌无力症状和低钾血症。但过量补钾治疗会导致TPP患者出现急性反跳性高钾血症,再次威胁患者的健康。本文报道了3例TPP患者因过量补钾治疗而导致急性反跳性高钾血症,分析引起反跳性高钾血症的危险因素,希望为TPP患者的临床治疗提供更多资料。Thyrotoxic periodic paralysis(TPP)is an endocrine emergency caused by thyrotoxicosis,mainly manifesting as periodic muscle weakness and hypokalemia,which seriously threatens the health of patients.The level of hypokalemia is closely related to the severity of muscle weakness in patients with TPP,and potassium supplementation can quickly alleviate the symptom of muscle weakness and hypokalemia.However,excessive potassium supplementation can lead to acute rebound hyperkalemia in patients with TPP,which also threatens the health of patients.This article reported 3 cases of TPP patients with acute rebound hyperkalemia caused by excessive potassium supplementation,and analyzed the risk factors for rebound hyperkalemia,in order to provide more information for the clinical treatment of TPP patients.

关 键 词：甲状腺毒性周期性麻痹 麻痹 高钾血性周期性 低钾性周期性麻痹 低钾血症 反跳性高钾血症 病例报告 

分 类 号：R685.9[医药卫生—骨科学]