Silicon-substituted rhodamines for stimulated emission depletion fluorescence nanoscopy  

作　　者：Ning Wang Yumeng Hao Xiaowei Feng Haidan Zhu Dazhi Zhang Ting Wang Xiaoyan Cui 

机构地区：[1]Department of Chemistry,School of Chemistry and Molecular Engineering,East China Normal University,Shanghai 200241,China [2]Department of Organic Chemistry,College of Pharmacy,Naval Medical University(Second Military Medical University),Shanghai 200433,China

出　　处：《Chinese Chemical Letters》2022年第1期133-140,共8页中国化学快报（英文版）

基　　金：supported by the Natural Science Foundation of Shanghai(Nos.19ZR1480000,20ZR1470200);National Natural Science Foundation of China(No.81830106);the Program for Professor of Special Appointment(Eastern Scholar,No.TP2017039)。

摘　　要：As an essential part in the toolbox of super-resolution microscopy,stimulated emission depletion(STED)nanoscopy has been widely explored in revealing the substructure and bioactivities in fluorescence imaging.Among the applied STED fluorophores,silicon-substituted rhodamines(SiRs)belong to one of the most extensively employed fluorophores.The carboxy-SiR was favored in STED bioimaging with many advantages,including reliable photostability,cell permeability,tunable fluorogenicity,feasible structural decoration and so on.We reviewed the research of carboxy-SiR in the STED nanoscopy and hopefully this can inspire more efforts in the design and application of STED fluorophores.

关 键 词：Silicon XANTHENE SUPER-RESOLUTION Stimulated emission depletion 

分 类 号：O657.3[理学—分析化学]