术中使用琥珀酰明胶注射液致过敏性休克罕见病例的原因分析及其治疗对策  

Etiological Analysis of a Rare Case with Anaphylactic Shock Caused by Succinylated Gelatin Injection in Surgery and Its Treatment Strategy

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作  者:姜英凤[1] 石祥奎 张静[1] JIANG Ying-feng;Shi Xiang-kui;ZHANG Jing(Department of Pharmacy,Xuzhou Maternity and Child Health Care Hospital,Pharmacy Jiangsu 221000,China)

机构地区:[1]徐州市妇幼保健院药事科,江苏徐州221000

出  处:《抗感染药学》2021年第12期1816-1818,共3页Anti-infection Pharmacy

摘  要:目的:分析术中使用琥珀酰明胶注射液致过敏性休克罕见病例的病理机制及其治疗对策。方法:临床药师通过分析术中使用琥珀酰明胶注射液后发生过敏性休克病例的相关病情,结合相应文献资料,探究该不良事件的病理机制和治疗对策。结果:术中过敏性休克为琥珀酰明胶注射液所致的罕见严重的不良反应,建议及时停用琥珀酰明胶注射液并抢救治疗后患者逐渐恢复、好转,完成手术。结论:通过临床药师在该例术中药物不良反应的分析和处置中的积极参与,手术顺利完成,避免了更严重后果的发生。Objective: To analyze the pathogenesis of a rare case with anaphylactic shock caused by succinylated gelatin injection in surgery and its treatment strategy. Methods: Through analyzing the conditions of patients with anaphylactic shock after using succinylated gelatin injection in surgery and searching related literature, the pathogenesis and its treatment strategy was explored. Results: Intraoperative anaphylactic shock was a rare and serious adverse drug reaction caused by succinylated gelatin injection. It was recommended to stop succinylated gelatin injection in time and the patient gradually recovered and improved after rescue treatment to complete the operation. Conclusion: Through the active participation of clinical pharmacists in the analysis and treatment of intraoperative adverse drug reactions, the operation is successfully completed and more serious consequences are avoided.

关 键 词:琥珀酰明胶 过敏性休克 药品不良反应 治疗对策 

分 类 号:R969.3[医药卫生—药理学]

 

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