早期免疫营养支持联合激励式护理对喉癌全喉切除术患者的影响  

Effect of early immune nutrition support combined with incentive nursing on patients with laryngeal cancer undergoing total laryngectomy

作　　者：陈海芳 马灵草[1] 戴晗青 董婷 CHEN Haifang;MA Lingcao;DAI Hanqing;DONG Ting(Henan Provincial People’s Hospital,Zhengzhou,450000,China)

机构地区：[1]河南省人民医院耳鼻咽喉头颈外科,河南省郑州市450000

出　　处：《护理实践与研究》2022年第8期1214-1218,共5页Nursing Practice and Research

摘　　要：目的 探究早期免疫营养支持联合激励式护理对喉癌全喉切除患者免疫功能、营养状况及心理状态的影响。方法 以 2019 年 6 月—2020 年 8 月耳鼻喉科收治的 80 例喉癌行全喉切除患者为研究对象,按照两组基础资料具有可比性的原则分为观察组与对照组,各 40 例。对照组进行常规护理干预,观察组进行早期免疫营养支持和激励式护理,干预时间为 15 d,比较两组患者干预前后免疫功能、营养状况及心理状态的差异。结果 干预前两组患者焦虑、抑郁评分比较,差异无统计学意义(P>0.05);干预后观察组焦虑、抑郁评分低于对照组,组间比较差异有统计学意义(P<0.05)。干预前,两组患者免疫球蛋白 IgA、IgG、IgM 以及 T 淋巴细胞 CD3^(+)、CD4^(+)和 CD4^(+)/CD8^(+)水平值比较,差异均无统计学意义(P>0.05);干预后观察组免疫球蛋白 IgA、IgG、IgM 以及 T 淋巴细胞 CD3^(+)、CD4^(+) 和 CD4^(+)/CD8^(+)水平值均高于对照组,组间比较差异有统计学意义(P<0.05)。干预前,两组患者血红蛋白、血清白蛋白和前白蛋白水平比较差异均无统计学意义(P>0.05);干预后观察组血红蛋白、血清白蛋白和前白蛋白水平均高于对照组,差异有统计学意义(P<0.05)。结论 对喉癌全喉切除患者进行早期免疫营养支持联合激励式护理干预,可有效减轻患者焦虑、抑郁情绪,促进患者免疫功能和营养状况的改善。Objective To explore the effects of early immune nutrition support combined with incentive nursing on immune function,nutritional status and psychological state of patients with laryngeal cancer after total laryngectomy.Methods A total of 80 patients with laryngeal cancer who underwent total laryngectomy in the department of otolaryngology from June 2019 to August 2020 were selected as the study objects.According to the principle of comparability of the basic data of the two groups,and they were divided into an observation group and a control group,with 40 cases in each group.The control group was given routine nursing intervention,and the observation group was given early immune nutrition support and incentive nursing.The intervention time was15 days.The differences in immune function,nutritional status and psychological state of the two groups before and after the intervention were compared.Results Before intervention,there were no significant differences in the scores of anxiety and depression between the two groups(P>0.05).After intervention,the scores of anxiety and depression in the observation group were lower than those in the control group,and the differences between the groups were statistically significant(P <0.05).Before intervention,there were no significant differences in the levels of immunoglobulin IgA,IgG,IgM,and T lymphocyte CD3^(+),CD4^(+),and CD4^(+)/CD8^(+) between the two groups(P>0.05).After intervention,the levels of immunoglobulin IgA,IgG,IgM,and T lymphocyte CD3^(+),CD4^(+),and CD4^(+)/CD8^(+) in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P <0.05).Before intervention,there were no significant differences in the levels of hemoglobin,serum albumin and prealbumin between the two groups(P >0.05).After intervention,the levels of hemoglobin,serum albumin and prealbumin in the observation group were higher than those in the control group,and the differences were statistically significant(P <0.05).Conclu

关 键 词：喉癌 全喉切除术 早期免疫营养支持 激励式护理 免疫功能 营养状况 心理状态 

分 类 号：R473.6[医药卫生—护理学]