Wearable Sweat Biosensors Refresh Personalized Health/Medical Diagnostics  

作　　者：Wenhui Ji Jingyu Zhu Wanxia Wu Nanxiang Wang Jiqing Wang Jiansheng Wu Qiong Wu Xuewen Wang Changmin Yu Gaofeng Wei Lin Li Fengwei Huo 

机构地区：[1]Key Laboratory of Flexible Electronics&Institute of Advanced Materials,Nanjing Tech University,Nanjing 211816,China [2]Frontiers Science Center for Flexible Electronics,Xi’an Institute of Flexible Electronics(IFE)and Xi’an Institute of Biomedical Materials&Engineering,Northwestern Polytechnical University,Xi’an 710072,China [3]Naval Medical Department,Naval Medical University,Shanghai 200433,China [4]The Institute of Flexible Electronics(IFE,Future Technologies),Xiamen University,Xiamen 361005,China

出　　处：《Research》2022年第1期157-175,共19页研究（英文）

基　　金：supported by the National Key R&D Program of China(2020YFA0709900);the National Science Fund for Distinguished Young Scholars(21625401);the National Natural Science Foundation of China(22077101,21701086,21727808);the Joint Research Funds of Department of Science&Technology of Shaanxi Province and Northwestern Polytechnical University(2020GXLH-Z-008);the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2020WNLOKF023);the ChinaSweden Joint Mobility Project(51811530018);the Natural Science Basic Research Program of Shaanxi(Program No.2019JLZ-11);the Fundamental Research Funds for the Central Universities Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX21_1100)。

摘　　要：Sweat contains a broad range of critical biomarkers including ions,small molecules,and macromolecules that may indirectly or directly reflect the health status of the human body and thereby help track disease progression.Wearable sweat biosensors enable the collection and analysis of sweat in situ,achieving real-time,continuous,and noninvasive monitoring of human biochemical parameters at the molecular level.This review summarizes the physiological/pathological information of sweat and wearable sweat biosensors.First,the production of sweat pertaining to various electrolytes,metabolites,and proteins is described.Then,the compositions of the wearable sweat biosensors are summarized,and the design of each subsystem is introduced in detail.The latest applications of wearable sweat biosensors for outdoor,hospital,and family monitoring are highlighted.Finally,the review provides a summary and an outlook on the future developments and challenges of wearable sweat biosensors with the aim of advancing the field of wearable sweat monitoring technology.

关 键 词：thereby summarized enable 

分 类 号：TP212.3[自动化与计算机技术—检测技术与自动化装置] TS106[自动化与计算机技术—控制科学与工程]