Comparison of fundus fluorescein angiography and fundus photography grading criteria for early diabetic retinopathy  

作　　者：Xin-Yue Li Shu Wang Li Dong Hong Zhang 

机构地区：[1]Eye Hospital,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,Heilongjiang Province,China [2]Eye Department,Shanghai Children's Hospital,Shanghai Jiao Tong University,Shanghai 200062,China

出　　处：《International Journal of Ophthalmology(English edition)》2022年第2期261-267,共7页国际眼科杂志（英文版）

基　　金：Supported by National Natural Science Foundation of China (No.U20A20363,No.81970776,No.81671844);Special Fund of the Academy of Medical Sciences of Heilongjiang Province for Scientific Research (No.CR201809);Natural Science Foundation of Heilongjiang Province,China (No.LH2020H039);Higher Education Reform Project of Heilongjiang Province,China (No.SJGY20180332);Heilongjiang Provincial Postdoctoral Research Fund (No.LBH-Z18221)。

摘　　要：AIM:To compare the assessment outcomes of the characteristics of mild to moderate non-proliferative diabetic retinopathy(NPDR) established by fundus photography and fundus fluorescein angiography(FFA).METHODS:The fundus photos and FFA results of 260 patients with diabetes mellitus were reviewed.Diabetic retinopathy(DR) severity was graded based on the international classification standard.The microaneurysms,hemorrhages,and intraretinal microvascular abnormalities(IRMA) in FFA images of patients with mild to moderate NPDR were observed.The differences between the fundus photos and the FFA results were summarized,analyzed,and compared.RESULTS:The counting of intraretinal hemorrhages identified by FFA revealed that only 9 eyes(1.9%) had more than 20 intraretinal hemorrhages in all four quadrants;15 eyes(3.1%) had more than 20 intraretinal hemorrhages in three quadrants;26 eyes(5.4%) had over 20 intraretinal hemorrhages in two quadrants;and 37 eyes(7.7%) had more than 20 intraretinal hemorrhages in only one quadrant.Furthermore,the number of IRMAs appeared ≥4 in 17 eyes,3 in 35 eyes,2 in 69 eyes,and 1 in 93 eyes.CONCLUSION:FFA has higher detection accuracy of retinal angiopathy than fundus photography.FFA grading results are helpful for timely detection and proper treatment of lesions easily missed by fundus photography.

关 键 词：diabetic retinopathy fundus fluorescein angiography grading criteria 

分 类 号：R587.2[医药卫生—内分泌] R774.1[医药卫生—内科学]