中国儿科药品常用剂型研究进展及前景分析  

Research progress and prospect analysis of common dosage forms of pediatric drugs in China

作　　者：李宁 蒋境兴 武英茹 兰子君 郭福贵 程玉钏[1,2,3] 倪艳 LI Ning;JIANG Jingxing;WU Yingru;LAN Zijun;GUO Fugui;CHENG Yuchuan;NI Yan(Shanxi Provincial Institute of Traditional Chinese Medicine,Taiyuan 030012,China;Shanxi Province Traditional Chinese Medicine Preparation Technology Development Laboratory,Taiyuan 030012,China;Provincial Key Cultivation Laboratory for Key Technology Development of New Traditional Chinese Medicine Products,Taiyuan 030012,China;Shanxi University of Traditional Chinese Medicine,Taiyuan 030619,China)

机构地区：[1]山西省中医药研究院,山西太原030012 [2]山西省中药制剂成型技术开发实验室,山西太原030012 [3]中药新产品关键技术开发省级重点培育实验室,山西太原030012 [4]山西中医药大学,山西太原030619

出　　处：《药物评价研究》2022年第1期193-200,共8页Drug Evaluation Research

基　　金：山西省重点研发项目(201603D321028);山西省“四个一批”科技兴医创新计划项目(2020SYS09);山西省医学重点科研项目计划重点攻关专项(2021XM32)。

摘　　要：我国儿科药品剂型较丰富,但是常用药物种类及规格仍无法满足日益增长的用药需求。综述我国儿科药品常用剂型种类及其应用现状,发现儿童常用药物剂型有片剂、颗粒剂、注射剂等,口服剂型所面临的主要问题是口感差、用药依从性低;非口服剂型用药依从性相对较高,但儿童用产品较少,需大力开发。针对各剂型研发所面临的机遇及挑战,未来儿童用药首选剂型仍是口服制剂,但是会向微片、微丸、分散片的形式发展。China's pediatric drug dosage form is relatively rich,but the types and specifications of commonly used medicines still cannot meet the increasing demand for medicines.The author reviewed the types of commonly used pediatric drugs and their application status in China,and found that the commonly used drug forms for children include tablets,granules,injections,etc.The main problems faced by oral dosage forms are poor taste and low medication compliance;the compliance of non-oral dosage forms medication is relatively high,but there are few products for children,which need to be developed vigorously.In view of the opportunities and challenges faced by the development of various dosage forms,the preferred dosage form for children's medicine in the future will still be oral preparations,but will develop into the form of microtablets,pellets,and dispersible tablets.

关 键 词：儿科剂型 儿童用药 用药依从性 微片 微丸 分散片 经皮给药 

分 类 号：R944.5[医药卫生—药剂学]