颈动脉内-中膜厚度对冠状动脉粥样硬化病变的诊断价值  

The diagnostic value of carotid intima-media thickness for coronary atherosclerotic lesions

作　　者：李余良 吴红莲 郝传伟 Li Yuliang;Wu Honglian;Hao Chuanwei(The Dongguan Sanju Hospital,Dongguan,Guangdong 523710)

机构地区：[1]东莞三局医院,广东东莞523710

出　　处：《基层医学论坛》2022年第7期103-105,共3页The Medical Forum

摘　　要：目的探讨颈动脉内-中膜厚度(IMT)对冠状动脉粥样硬化病变的诊断价值。方法选择2019年6月—2020年11月就诊于东莞三局医院的50例冠心病患者,设为观察组(冠状动脉狭窄率<50%22例,冠状动脉狭窄率≥50%28例;冠状动脉病变支数:多支病变19例,双支病变15例,单支病变16例),选择同期就诊于该院的50例非冠心病患者为对照组,测量IMT。比较2组IMT差异和不同冠状动脉狭窄率、冠状动脉病变支数冠心病患者IMT、Gensini评分差异,分析IMT与Gensini评分的相关性,并绘制受试者工作特征(ROC)曲线,分析IMT诊断冠状动脉粥样硬化病变的价值。结果观察组IMT高于对照组,有统计学差异(P<0.05);冠状动脉狭窄率≥50%组IMT、Gensini评分均高于冠状动脉狭窄率<50%组,有统计学差异(P<0.05);单支病变组IMT、Gensini评分高于双支病变组、多支病变组,且双支病变组IMT、Gensini评分高于多支病变组,有统计学差异(P<0.05);IMT与Gensini评分呈正相关(P<0.05);IMT诊断冠状动脉粥样硬化病变的AUC为0.734(95%CI:0.615~0.874),诊断敏感度为88.92%,特异度为92.14%。结论IMT可预测冠状动脉粥样硬化病变严重程度,临床诊断价值较高。Objective To investigate the diagnostic value of carotid intima-media thickness(IMT)for coronary atherosclerotic lesions.Methods Fifty patients with coronary artery disease who visited our hospital from June 2019 to November 2020 were selected as the observation group(22 patients with coronary artery stenosis<50%and 28 patients with coronary artery stenosis≥50%;number of coronary artery lesions:19 patients with multivessel disease,15 patients with double vessel disease,and 16 patients with single vessel disease),and 50 non coronary patients who visited our hospital during the same period were selected as the control group to measure IMT.To compare the difference of IMT between the two groups and the difference of IMT and Gensini scores between different coronary artery stenosis rates and numbers of coronary artery lesion branches in patients with coronary artery disease,we analyzed the correlation between IMT and Gensini scores,and plotted the receiver operating characteristic(ROC)curve to analyze the value of IMT in diagnosing coronary atherosclerotic lesions.Results The IMT of the observation group was higher than that of the control group,with statistical difference(P<0.05),and the scores of IMT and Gensini in the group with coronary artery stenosis≥50% were higher than those in the group with coronary artery stenosis<50%,with statistical difference(P<0.05).The scores of IMT and Gensini in the single vessel disease group were higher than those in the two-vessel disease group and the multi-vessel disease group,and the scores of IMT and Gensini in the two-vessel disease group were higher than those in the multi-vessel disease group,with statistical difference(P<0.05).The IMT was positively correlated with the Gensini score(P<0.05),the AUC of coronary atherosclerotic lesions was 0.734(95%CI:0.615~0.874),the diagnostic sensitivity was 88.92% and the specificity was 92.14%.Conclusion IMT can predict the severity of coronary atherosclerotic lesions and is of high value in the diagnosis of coronary atheroscleroti

关 键 词：冠状动脉粥样硬化病变 冠心病 颈动脉内-中膜厚度 冠状动脉造影 GENSINI评分 

分 类 号：R541.4[医药卫生—心血管疾病]